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Saxenda

Weight Loss | Active ingredient(s): Liraglutide | Manufacturer: Novo Nordisk

Week 1 = 0.6mg daily
week 2 = 1.2mg daily
week 3 = 1.8mg daily
week 4 = 2.4mg daily
week 5 onwards = 3mg daily

When you start: one pen lasts 17 days.
When at the 3mg dosage: each pen lasts six days.

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  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How does Saxenda work?

The active ingredient liraglutide is present in a solution and applied with a pre-filled injection pen. Liraglutide is an acylated human glucagon-like peptide-1 (GLP-1) receptor agonist which is a synthetic version of the naturally produced GLP-1. Receptors for GLP-1 are located in various locations in the brain and activated by liraglutide which influences appetite regulation and calorie intake.

Liraglutide also helps improve blood glucose level regulation as it influences the secretion of insulin and glucagon. Despite this the medicine is not suitable as sole medication for diabetes.

Who can buy Saxenda online?

Saxenda helps to aid sustainable weight loss in patients suffering from obesity with a Body Mass Index (BMI) of above 30 or 27 and higher when there a weight-related comorbid conditions such as high blood pressure, diabetes or dyslipidemia is present.

If the patient hasn't lost at least 5% of their initial body weight after 12 weeks of using the standard dose of 3 mg per day, the treatment should be discontinued.

How do you use Saxenda?

A pre-filled pen contains the active ingredient liraglutide which can be applied in selected doses. The starting doses should be set at 0.6 mg. This is increased each following week by 0.6 mg until the final dose of 3 mg is reached. The slow increase helps to avoid side effects such a nausea while the body gets accustomed to the medication.

Construction Saxenda Pen Injection Liraglutide Weight Loss

The injection should be done only subcutaneously and can take place on the thigh, abdomen or arm. While the time of application can be chosen individually, it is recommended to inject Saxenda around the same time daily.

Saxenda is delivered with single-use needles which need to be disposed of after each use to avoid contamination. An appropriate disposal box is included. The pen is stored without a needle attached.

Saxenda dosage guide

How should you store Saxenda?

Due to the active ingredient being applied with a solution Saxenda has to be stored in specific ways to ensure a safe maintenance of the medication. Saxenda has to be continuously stored in the refrigerator at temperatures between 2°C and 8°C. However, it should be taken care that the solution is not stored near or in the freezer compartment to avoid it from being at too low temperatures. After the first application the solution in the pen can be safely used for up to a month.

The solution should be protected from direct light to avoid deterioration, so the the cap should be placed back on the pen after every use. Before use the solution should be checked if it's clear and colourless or almost colourless. In case Saxenda has been frozen at any point it should not be used anymore.

Are there any side effects?

As with any prescription medication Saxenda may also cause unwanted side effects. Especially when starting the treatment and the body is still adapting to the medication, side effects such as nausea are known to appear. In most cases these side effects abate on their own without the need to adjust the dosage. Most common side effects for Saxenda also include diarrhoea, constipation, headaches and vomiting.

Less common side effects of Saxenda can include reduced blood sugar, stomach pain, dizziness, tiredness, changing lipase levels. Due to the mode of application there is also an increased risk for local reactions. These might include rash, erythema and pruritus.

As Saxenda might also cause serious side effects such as dehydration, increasing heart rate, pancreatitis, thyroid and acute gallbladder disease. Should any of these or side effects develop, the treatment should be discontinued and a doctor contacted as soon as possible.

What are the contraindications and interactions of Saxenda?

Saxenda is unsuitable for weight loss treatment in patients with hypersensitivity to liraglutide or any other components of the product. Patients younger than 18, older than 75 or with a BMI below 30 or under 27 with comorbid conditions are also not suited for treatment with Saxenda. The medication should not be used during pregnancy and breastfeeding.

Further contraindications are:

  • congestive heart failure
  • inflammatory bowel disease
  • mild to moderate hepatic impairment
  • severe renal or hepatic impairment
  • medullary thyroid carcinoma (MTC)
  • Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

It is important to note that medical treatment alone is not sufficient for a sustainable reduction of weight. Saxenda therefore needs to be treated merely as an additional helper complementing healthy eating and sufficient physical exercise. If the problems with excess weight are primarily caused by issues eating disorders, endocrinological dysfunctions or as medication side effects, Saxenda is not recommended as treatment.

For patients with a medical history of depression or suicidal ideation, Saxenda is not a recommended treatment as it increases the risk for suicidal thoughts and behaviour. Due to this, patients should be especially observant of irregular mood and behavioural changes.

Interactions

Although liraglutide aids regulation of blood glucose levels, it is not suitable as a stand-alone treatment for type-2 diabetes. It should also not be used in conjunction with insulin or other GLP-1 receptor agonists.

When combining Saxenda with other weight loss medication of any kind, there is a higher risk for side effects. Therefore other potentially used treatments should be stopped before beginning the application of Saxenda.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
Is the price all-inclusive?
Can I place more than one order at a time?
What are my delivery options?
Is it safe to buy prescription medication online?
How do I know which treatment is best for me?
Is this service discreet?
What is included in the online consultation?

Our consultations include general questions about your health (e.g. blood pressure levels, current and past conditions), as well as specific questions related to your selected treatment. We will also request relevant personal information to complete payment and delivery.

All questions are necessary, and your answers and details will not be shared with any third-parties. Only our doctors have access to your medical information.

Will a doctor review my consultation?

It is a legal and medical requirement that a doctor first reviews all completed consultations. We have a team of in-house doctors and specialists who will ensure your selected treatment is safe for your use. All information is stored securely and confidentially.

Please note, we do not guarantee that our doctors will approve treatment.

What happens after I submit my order?

Your consultation will be sent directly to our medical team, where it will be reviewed by one of our doctors.

If your chosen treatment is deemed suitable for your use, they will issue a prescription. Your prescription is then forwarded to our pharmacy, where your medication will be dispensed and dispatched for courier delivery.

Is the price all-inclusive?

Yes. All 121doc orders include a medical consultation, a prescription and next-day delivery. There are no additional costs. We believe in providing a safe and easy-to-use service.

Can I place more than one order at a time?

Yes. However, certain medications may negatively interact with each other. Our doctors may not approve your order on this basis.

You can place multiple items in one basket, and complete a consultation for all.

If you wish to place a second order for a different medication, you will have to complete a separate consultation.

What are my delivery options?

We offer several delivery options:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not available, a friend or relative can sign in your place.

None of these options will incur an additional charge.

Is it safe to buy prescription medication online?

To ensure you are purchasing from a reputable company, you should look to see their country’s regulatory bodies verify them.

In the UK, this is the Care Quality Commission (CQC) and the Medicines and Healthcare products Regulatory Agency (MHRA).Certificates can be viewed here.

How do I know which treatment is best for me?

Some treatments also offer the 'Advise Me' function. You will be asked questions about your lifestyle and needs, plus medical questions. You will then be presented with the advice of our doctors.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also regularly inspected by various UK regulatory agencies, such as the Information Commissioner's Office (ICO).

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

Comparison

  Pack contains 84 Xenical® 120mg Orlistat oral hard capsulesBox of Mysimba 8mg/90mg naltrexone/bupropion hydrochloride 112 prolonged-release tablets
XenicalMysimba
  Overview
Overview Weight loss tabletsWeight loss tablets
  Active ingredient(s)
Active ingredient(s) OrlistatNaltrexone & bupropion
  Who can take it
Who can take it BMI over 30 (or 27)BMI over 30 (or 27)
  Features
Features Reduces dietary fat absorption Reduces appetite & increases energy expenditure
  Breastfeeding
Breastfeeding UnsuitableUnsuitable
  Pregnant
Pregnant Not recommendedNot recommended
  Application
Application TabletTablet
  How to take
How to take 3 daily tabletsDaily tablet(s)
  Price
Price £79.99£134.99
 
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