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Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.
The active ingredient liraglutide is present in a solution and applied with a pre-filled injection pen. Liraglutide is an acylated human glucagon-like peptide-1 (GLP-1) receptor agonist which is a synthetic version of the naturally produced GLP-1. Receptors for GLP-1 are located in various locations in the brain and activated by liraglutide which influences appetite regulation and calorie intake.
Liraglutide also helps improve blood glucose level regulation as it influences the secretion of insulin and glucagon. Despite this the medicine is not suitable as sole medication for diabetes.
Saxenda helps to aid sustainable weight loss in patients suffering from obesity with a Body Mass Index (BMI) of above 30 or 27 and higher when there a weight-related comorbid conditions such as high blood pressure, diabetes or dyslipidemia is present.
If the patient hasn't lost at least 5% of their initial body weight after 12 weeks of using the standard dose of 3 mg per day, the treatment should be discontinued.
A pre-filled pen contains the active ingredient liraglutide which can be applied in selected doses. The starting doses should be set at 0.6 mg. This is increased each following week by 0.6 mg until the final dose of 3 mg is reached. The slow increase helps to avoid side effects such a nausea while the body gets accustomed to the medication.
The injection should be done only subcutaneously and can take place on the thigh, abdomen or arm. While the time of application can be chosen individually, it is recommended to inject Saxenda around the same time daily.
Saxenda is delivered with single-use needles which need to be disposed of after each use to avoid contamination. An appropriate disposal box is included. The pen is stored without a needle attached.
Due to the active ingredient being applied with a solution Saxenda has to be stored in specific ways to ensure a safe maintenance of the medication. Saxenda has to be continuously stored in the refrigerator at temperatures between 2°C and 8°C. However, it should be taken care that the solution is not stored near or in the freezer compartment to avoid it from being at too low temperatures. After the first application the solution in the pen can be safely used for up to a month.
The solution should be protected from direct light to avoid deterioration, so the the cap should be placed back on the pen after every use. Before use the solution should be checked if it's clear and colourless or almost colourless. In case Saxenda has been frozen at any point it should not be used anymore.
As with any prescription medication Saxenda may also cause unwanted side effects. Especially when starting the treatment and the body is still adapting to the medication, side effects such as nausea are known to appear. In most cases these side effects abate on their own without the need to adjust the dosage. Most common side effects for Saxenda also include diarrhoea, constipation, headaches and vomiting.
Less common side effects of Saxenda can include reduced blood sugar, stomach pain, dizziness, tiredness, changing lipase levels. Due to the mode of application there is also an increased risk for local reactions. These might include rash, erythema and pruritus.
As Saxenda might also cause serious side effects such as dehydration, increasing heart rate, pancreatitis, thyroid and acute gallbladder disease. Should any of these or side effects develop, the treatment should be discontinued and a doctor contacted as soon as possible.
Saxenda is unsuitable for weight loss treatment in patients with hypersensitivity to liraglutide or any other components of the product. Patients younger than 18, older than 75 or with a BMI below 30 or under 27 with comorbid conditions are also not suited for treatment with Saxenda. The medication should not be used during pregnancy and breastfeeding.
Further contraindications are:
It is important to note that medical treatment alone is not sufficient for a sustainable reduction of weight. Saxenda therefore needs to be treated merely as an additional helper complementing healthy eating and sufficient physical exercise. If the problems with excess weight are primarily caused by issues eating disorders, endocrinological dysfunctions or as medication side effects, Saxenda is not recommended as treatment.
For patients with a medical history of depression or suicidal ideation, Saxenda is not a recommended treatment as it increases the risk for suicidal thoughts and behaviour. Due to this, patients should be especially observant of irregular mood and behavioural changes.
Although liraglutide aids regulation of blood glucose levels, it is not suitable as a stand-alone treatment for type-2 diabetes. It should also not be used in conjunction with insulin or other GLP-1 receptor agonists.
When combining Saxenda with other weight loss medication of any kind, there is a higher risk for side effects. Therefore other potentially used treatments should be stopped before beginning the application of Saxenda.
Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.
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Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.
The consultation is completely free, and takes between 5 and 10 minutes of your time.
All your information is safe with us. We don’t share it with anyone unless you want us to.
If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.
As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.
If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.
Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).
Once our pharmacy receives your prescription, you will get a second email with your package tracking code.
All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.
We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.
With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).
All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.
With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.
The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.
There are two ways to subscribe. The first is during the order process. The second is via your profile here.
You can cancel or amend your repeat prescriptions at any time.
There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!
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