Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

Buying Doxycycline Online

You can buy Doxycycline online here without a face-to-face appointment. To start your course as soon as possible, complete a consultation before 4.30pm for free next day delivery across the country.

To ensure that our doctors have all the right information regarding your current health, we ask all our patients to complete a straightforward online consultation form, similar to questions you would be asked in-person during a doctor's appointment or STI check-up. A prescription for your chlamydia treatment will be sent straight to the pharmacy for speedy delivery. All orders with 121doc include a free consultation and next day delivery.

What is Doxycycline?

Doxycycline is a tetracycline antibiotic used to treat a number of bacterial infections, one of the most common being the STI chlamydia. It can also be used as a preventative treatment for malaria. Doxycycline is a versatile medication and can also cure non-specific urethritis, mycoplasma genitalium and ureaplasma urealyticum.

For treating the sexually transmitted infections, Doxycycline is highly effective at a success rate of 90% and easy-to-take over the course of just one week. This is a more appropriate medication option for individuals who are sensitive and experience side effects with high dosages of medications as each tablet is 100mg. Alternative treatment for chlamydia is Azithromycin, which is available in two tablets of 500mg each to be taken immediately. Both are effective and require you to refrain from sex for the following 14 days to ensure the antibiotics have worked. You can go for another free NHS STI check-up at your local sexual health clinic or GUM clinic to ensure the medication has been completely successful.

More About Chlamydia

Chlamydia is very common in the UK and completely curable with the right antibiotics. This is especially important for women as chlamydia is symptomless for the vast majority of male and females but may cause long-term difficulties without curing the infection, such as infertility and pelvic inflammatory disease (PID). For more information on chlamydia and the treatments available, visit our chlamydia information page.

How does Doxycycline work?

Doxycycline is classed as a tetracycline antibiotic meaning it is a four-ringed molecular structure. Tetracycline medications tend to be used to treat multiple bacterial infections that can include acne, urinary tract infections and a range of STIs. At 121doc, we prescribe Doxycycline for the treatment of the STIs mentioned above and malaria as a preventative treatment taken daily when you're visiting a country prone to the virus.

This highly effective chlamydia treatment that prevents the spread of bacteria that causes sexually transmitted infections. So it doesn't directly cure the infection but aids your body's immune system:

  1. Stops the production of protein that helps to spread the bacteria.
  2. This allows your body's immune system to attack the infection, which finally kills it.

How do you take Doxycycline?

Taking Doxycycline tablets is simple and 90% effective. Whilst this is a high percentage, it is advised to not have sexual intercourse for two weeks (14 days) after finishing the course to make sure the antibiotics have taken effect. You can also request an additional follow-up test to make sure the infection has cleared.

  • Take one tablet twice daily for a period of seven days
  • If you miss a dose, take your tablet as soon as you remember
  • Continue the whole course, even if you feel better

Doxycycline gets to work very quickly, but it's very important to remember to take this treatment every day, even if you start feeling better in order to treat chlamydia successfully. If you would like to take an STI test in order to see if the bacterium has been fully removed, it is recommended that you wait for a two-week period before doing so.

Doxycycline dosages for chlamydia

There is one optimum dose for chlamydia, non-specific urethritis, mycoplasma genitalium and ureaplasma urealyticum and that is 14 tablets at a 100mg dosage each. This dose is ideal if you tend to experience side effects with prescription medications.

Doxycycline Side Effects

This treatment is highly effective in a low dose and unlikely to cause serious side effects, which is why it is so widely prescribed. In fact, individuals that can't take high dosages such as Azithromycin will be prescribed Doxycycline. The most common effects may include diarrhoea, thrush, vomiting, heartburn, abdominal pain and sensitivity to light. If you're experiencing diarrhoea, it is often advised to steer clear of using diarrhoea tablets as these could make the side effect worse when taking Doxycycline as well.

These shouldn't be a cause for concern, but if these side effects persist or you start to develop anything more serious, you should seek medical help straight away.

An allergic reaction to Doxycycline needs prompt medical attention. Symptoms include a fever, hives, rash, joint pain and fatigue. This could also be a result of the body combatting the medication; a condition called autoimmune syndrome.

Women should also be aware that Doxycycline can reduce the effectiveness of your oral contraceptive, especially if it contains oestrogen. Please check with your doctor and use additional protection such as condoms for the remainder of that cycle.

Doxycycline Precautions

Doxycycline is used widely and is suitable for most people, however you will not be prescribed this if you are pregnant or breastfeeding. You should also not use this medication if you have sensitivity to doxycycline, minocycline or tetracycline. If you are currently taking vitamin or mineral supplements, you should mention this to your doctor, as these types of treatments have been known to render the drug less effective. This includes medications or supplements containing calcium, aluminium, magnesium and iron.

Regarding the sensitivity to light under Doxycycline side effects, exposure can cause a rash, redness or itching so try to refrain staying out in the direct sunlight and wear protective clothing.

Although this is rare, Doxycycline may cause intracranial hypertension in women who are overweight, childbearing age and there is a family history of the illness. Symptoms of intracranial hypertension include changes to your vision including blurred vision and headaches. If you're experiencing this, visit your doctor.

If you're experiencing symptoms of your infection, if this doesn't improve by the time the course is up, seek help from your doctor.

STI Protection

It's important to remember that you can get chlamydia and any other STIs again if you don't take the necessary precautions. The only contraception that diminishes your chances of catching infections is wearing a condom.

If you are sexually active, particularly with multiple partners, you can get tested for free at the appropriate STI Clinics or GUM Clinics across the UK. There might be a wait to be seen but the check-up is quick and you can get complete cover and free condoms too.

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How does it work?

Select Select your treatment


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Redeem your prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!