Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How does Kliovance work?

Women who reach menopause begin to produce less oestrogen naturally. The reduction in oestrogen levels in the blood stream can lead to a number of difficult symptoms. These symptoms can include hot flushes, irregular bleeding, vaginal itching, mood fluctuations and weight gain.

HRT is prescription medication that can help replace and maintain oestrogen levels in the blood. Supplementing oestrogen levels in this way can help to treat the symptoms associated with menopause, thus leading to a significant improvement in the quality of life.

The oestrogen in Kliovance helps alleviate these symptoms whilst the progestogen helps to balance this rise in oestrogen levels. Oestrogen can have a damaging impact on the womb lining. The progestogen helps protect the womb lining and so dramatically reduces the risk of any adverse reaction.

What are the benefits of Kliovance?

This is an effective treatment for the distressing symptoms of menopause that can occur due to decreased oestrogen production. Kliovance can help to maintain a healthy level of hormones in the blood stream and provide significant relief from menopausal symptoms.

Kliovance can also help minimise the increased risk of developing osteoporosis during menopause. The lack of oestrogen can lead to a weakening of bones, which increases the chances of them breaking. An increased level of oestrogen in the blood will reduce the risk of this occurring. Whilst this should not be a first line treatment for this condition, it can have a positive effect in dealing with it.

Who can use Kliovance?

As it contains both oestrogen and progestogen, women who have not had a hysterectomy can use Kliovance. If a hysterectomy has been completed, you may be more suitable for some of the oestrogen only HRT treatments. You can only buy Kliovance online if it has been recommended for you by your doctor. You should always consult with your doctor before deciding on a course of Kliovance. You will also need to have regular gynaecological check-ups when using this treatment to ensure that it is the right option for you.

As with all prescription medication, there are people who may not be suitable for Kliovance. This may not be the right treatment for you if you are sensitive to either oestrogen or progestogen. You may also not be suitable if you have a history of breast cancer, irregular vaginal bleeding, liver disease or circulatory issues. When you buy Kliovance online at 121doc, you will need to complete an online medical questionnaire.Our doctors will use the details that you provide to determine whether this is a suitable treatment option for you.

How to use this treatment?

Kliovance comes in a 1mg tablet that you are required to take once per day for the entirety of the 28-day cycle. The medication comes in a calendar marked pack, which is designed to help you keep track of your treatment. You should take each tablet with a glass of water as this will help reduce the possibility of indigestion and nausea. You can take each tablet with or without food.

To see the benefit of this medication, you should ensure that you take it as per the instructions. If you miss a day, you should not then take two tablets the following day. You should never exceed the 1mg dosage of Kliovance in a single day. You will be provided with a detailed patient leaflet, which will have information and instructions about this medication and how to use it. We require that you read this patient leaflet before beginning the treatment.

What are the Kliovance side effects?

The presence of progestogen in this treatment significantly reduces the risk of any side effects associated with oestrogen. This also means that women who have not had a hysterectomy can use Kliovance. As with other HRT treatments, there is the potential risk of side effects in very rare cases. These can include nausea, indigestion, headaches, fluid retention and leg cramps. Experiencing symptoms of this nature is often a sign that your body has begun adjusting to the treatment. If you experience anything more serious, you should inform your doctor. It is also important that your doctor monitors you whilst you are using HRT.

How to buy Kliovance online?

At 121doc, we understand that it can often be difficult finding the time to go see your doctor whenever you need a new pack of medication. You can buy Kliovance online by simply completing a medical questionnaire, which our doctors will use to determine whether this is the correct treatment option for you. Please find an alternative medication on our HRT treatment page if you find that Kliovance is not the correct medication for you. If the doctor approves your order, a prescription will be created and sent to our UK pharmacy to be dispensed on the same day. We offer next day delivery to all of our customers at no extra cost.


Evorel ContiPremiqueLivial
Overview Continuous combined HRT patchesContinuous combined HRT tabletsSynthetic HRT
Progestogen 170 mcg Norethisterone acetate every 24h1.5mg Medroxyprogesterone acetate-
Oestrogen 50 mcg Estradiol every 24h0.3mg Conjugated oestrogens-
  Active ingredient(s)
Active ingredient(s) Estradiol hemihydrate & Norethisterone acetateConjugated Oestrogens & Medroxyprogesterone acetate2.5mg Tibolone
  Who can take it
Who can take it If you are postmenopausalIf you are postmenopausalIf you are postmenopausal
Features ---
  Side effects
Side effects ---
  How to take
How to take 1 patch twice weeklyDaily tabletDaily tablet
  Price 3 month course
Price 3 month course £74.99£24.99£65.99
View treatmentView treatmentView treatment

What others say about us

4.6 score - 5981 Reviews

How does it work?

Select Select your treatment


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Redeem your prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!