Get the 121doc appReorder in just 3 clicks. It’s free
View

Nitrofurantoin

Cystitis|Active ingredient(s): Nitrofurantoin|Manufacturer: Various

Young woman holding a capsule and a glass of water on a light brown background.

Treat UTIs in 3 days: fast-acting and effective antibiotic

  • First-line treatment for cystitis.
  • Over 80% effective for UTIs.
  • Localised effect on your bladder, maximising effectiveness.
  • Effectively treats UTI in 3 days.
  • Low risk of side effects compared to other treatments.

How to take

Analogue wall clock on a white background.

Treats UTI in 3 days

Take one 100 mg Nitrofurantoin capsule twice daily for 3 days.

A close-up of a woman holding a glass of milk and a tablet.

Take with food or milk

You should take each capsule with food or milk. This boosts the effectiveness of your treatment.

A close-up of a woman refusing an alcoholic drink from a man.

Avoid alcohol

Avoid drinking excessive amounts of alcohol. It can irritate your bladder and make cystitis symptoms worse.

What others say about Nitrofurantoin

Trustpilot review
5 reviews with score 5

Quality healthcare
made easy

Price is all-inclusive.
Consultation is included.
Prescription is included.

Free shipping.
UK: Free next-day delivery.
Discreet packaging.

Licensed doctors.
Registered pharmacies.
Certified online pharmacy.

Nitrofurantoin

What is Nitrofurantoin?

Nitrofurantoin is an antibiotic which is prescribed to treat urinary tract infections (UTIs) in women. It is the first-line treatment for cystitis, and it works by killing the bacteria causing the infection.

It is available as modified-release 100 mg capsules. This means the medicine is released more gradually into your bloodstream, reducing the risk of side effects. You take one 100mg capsule twice daily for 3 days.

How does Nitrofurantoin work?

Nitrofurantoin capsules treat UTIs by targeting the bacteria causing the urinary tract infection.

It works by going inside the bacterial cells and damaging the genetic material inside. This kills the bacteria and treats the infection.

Nitrofurantoin is also particularly beneficial for UTIs, as the body usually flushes it out through your pee. This means it has a localised effect on the urinary tract, making it more effective at treating UTIs.

How effective is it?

Nitrofurantoin is an effective treatment for UTIs.

One clinical trial compared the effectiveness of Nitrofurantoin compared to a placebo (an inactive drug) in treating UTIs. They found:

  • Symptom improvement - 27 out of 35 women with UTI symptoms (77%) on Nitrofurantoin experienced significant symptom improvement in 3 days, compared to 19 out of 35 (54%) on the placebo.
  • Infection cured - 21 out of 26 women with a confirmed UTI (81%) on Nitrofurantoin were completely cured after 3 days, compared to 5 out of 25 (20%) on the placebo.

Studies also show that Nitrofurantoin causes fewer side effects than other UTI treatments.

How long does it take Nitrofurantoin to work?

Nitrofurantoin treats the infection in 3 days.

But you will start to feel better within 1-2 days. Even if you start to feel better, you must complete the entire course. This will prevent the infection from coming back.

If your symptoms do not go away after 3 days, you should see your doctor for advice.

Who can use Nitrofurantoin?

Most adult women can take Nitrofurantoin for cystitis. However, some women should not take it because they are more at risk of side effects.

Do not take Nitrofurantoin if you:

  • are in the final stages of pregnancy
  • are breastfeeding
  • are deficient in an enzyme called G6PD (glucose-6-phosphate dehydrogenase)
  • have severe kidney or liver problems
  • have acute porphyrias (a group of rare inherited disorders which affect your metabolism)

If you have any other medical conditions or are taking any other medications, consult your doctor before taking Nitrofurantoin.

Nitrofurantoin is not available online for UTIs in men. It is more complicated to treat in men, as it is often linked to an underlying condition. If you are a male and experiencing UTI symptoms, please consult your doctor to diagnose the issue.

How do I take Nitrofurantoin?

Take one 100 mg capsule twice daily for 3 days. You must complete the full course to ensure the infection does not return.

You should take the capsules with food or milk because it makes the medicine more effective.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed dose and take your next dose as scheduled.

Do not take a double dose to make up for a missed dose.

Can I drink alcohol on Nitrofurantoin?

It is safe to drink alcohol on Nitrofurantoin in moderation. However, it is not advised to drink too much as it can irritate the bladder and make symptoms of the UTI worse.

Are there any side effects?

Like all prescription medicines, Nitrofurantoin may cause side effects.

Side effects of Nitrofurantoin are rare (occurring in 1 in 1,000 people). These side effects may include:

  • feeling sick (nausea)
  • headache
  • diarrhoea
  • dizziness
  • drowsiness
  • fainting
  • loss of appetite

Read the patient information leaflet (PIL) for a full list of side effects.

Speak to your doctor as soon as possible if you experience any persistent or serious side effects. If you experience any serious side effects such as jaundice or a severe headache, please seek emergency medical attention.

Can Nitrofurantoin cause thrush?

Some women may experience thrush after a course of Nitrofurantoin. This is because sometimes antibiotics kill the normal, harmless bacteria which help to prevent fungal growth.

Does Nitrofurantoin make you urinate more?

No, Nitrofurantoin does not make you wee more. Weeing more often is likely a symptom of the UTI. However, if this symptom does not go away after you have finished treatment, you should speak to your doctor.

Can you take Paracetamol with Nitrofurantoin?

Yes, you can take paracetamol with Nitrofurantoin to help relieve symptoms of a UTI. But always make sure it's safe with a doctor or pharmacist if you have any other medical conditions or take any other medicines.

Is Nitrofurantoin safe?

Yes, Nitrofurantoin is a safe and clinically-proven treatment for cystitis and UTIs. But if you have another medical condition or take other medication, your doctor will need to ensure it’s safe for you. Our doctors will also know whether it’s safe for you based on your medical questionnaire during the ordering process.

Can I get Nitrofurantoin without a prescription?

Safety is our number one priority at 121doc. For this reason, our doctors will only prescribe treatment if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects
Medical review byDr. Caroline FontanaLast review 12 November 2025
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Nitrofurantoin Overview

Type of medicine Antibiotics
Used for Cystitis (urinary tract infections)
Active ingredient Nitrofurantoin
Works by Killing the bacteria causing the infection
Effective within 3 days
Available as Modified-release capsules
Available dosages 100 mg
Usage instructions Take one capsule twice daily for 3 days.
Packaging Foil blister packs containing capsules in a cardboard carton
Manufacturer Various
Branded available? No

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

Other treatments that might interest you

Contraceptive pills, ring and patch

We offer many contraceptive treatments and advice on the best fit for you.

  • All popular contraceptives
  • Home delivery
  • Delivered to your door tomorrow

Various treatments available

Get your Hormone Replacement Therapy easily online.

  • Many treatments available
  • Home delivery
  • Delivered to your door tomorrow

How does it work?

Select
Select Select your treatment and complete our online consultation.
Free consultation

Conditions:

Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.

Treatments:

If you know what you want, the quickest way to find a specific medication is to use the search bar here.

Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
Prescribe Our doctors review your order.
Free prescription

Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat
Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off

Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!