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Malaria | Active ingredient(s): Doxycycline hyclate | Manufacturer: Actavis

For STIs: take one tablet twice a day, for seven days.
For malaria: take one tablet per day. Start 2 days before traveling, and continue for 28 days after returning.

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  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How does it work?

Doxycycline is a tetracycline antibiotic used to treat a number of bacterial infections, one of the most common being the STI chlamydia. It can also be used as a preventative treatment for malaria. Doxycycline is a versatile medication and can also cure non-specific urethritis, mycoplasma genitalium and ureaplasma urealyticum.

The highly effective chlamydia treatment prevents the spread of bacteria causing sexually transmitted infections by inhibiting the production of a protein which helps the bacteria to reproduce. This allows the body's immune system to attack the infection, which finally kills it.

In malaria prevention, doxycycline targets the malaria parasite directly by preventing its protein production. This stops the parasite from reproducing and thus hinders it from manifesting an infection. If the parasite can't spread, the immune system can rapidly remove it from the body avoiding serious health implications for travellers.

Who can take it?

Doxycycline is used widely and is suitable for most people, however you will not be prescribed this if you are pregnant or breastfeeding. You should also not use this medication if you have sensitivity to doxycycline, minocycline or tetracycline.

If you are currently taking vitamin or mineral supplements, you should mention this to your doctor, as these types of treatments have been known to render the drug less effective. This includes medications or supplements containing calcium, aluminium, magnesium and iron.

How do you take it?

Depending on which condition you want to treat, there are different guidelines to follow regarding the course of your treatment with doxycycline. 121doc prescribes this antibiotic for malaria prevention and to treat chlamydia, please find all information on how to treat these conditions with doxycycline below.

Doxycycline as part of the malaria prevention therapy

This treatment should be started two days before you leave for a region with a high malaria risk as part of your travels. The treatment should be continued for the duration of your stay and up to four weeks afterwards. It is vital to remember to take your prescribed dosis every day to ensure that the level of Doxycycline remains high enough in your system to avoid infection. Malaria can remain in your system for a long time without causing you to feel ill, which is why you may be advised to continue taking your medication after your return.

Doxycycline: course of treatment against chlamydia

Doxycycline is commonly prescrived to treat sexually transmitted infections such as chlamydia. The medication is normally prescribed in a standard dose for chlamydia, non-specific urethritis, mycoplasma genitalium and ureaplasma urealyticum of 14 tablets containing 100mg of the active ingredient each.

If not otherwise advised by your doctor, you should take doxycycline according to the following instructions:

  • Take one tablet twice daily for a period of seven days
  • If you miss a dose, take your tablet as soon as you remember
  • Continue the whole course, even if you feel better

Doxycycline is likely to improve your symptoms quickly, but in order to treat chlamydia successfully, it is very important to remember to take the full course of the prescribed treatment, even if you start feeling better.

You should not have sexual intercourse for two weeks (14 days) after finishing the course of treatment to make sure the antibiotics have taken effect. You can also request an additional follow-up test to make sure the infection has cleared but it is recommended that you wait for a two-week period before doing so.

STI Protection

It is important to remember that you can get chlamydia and any other STIs again if you don't take the necessary precautions. The recommended measure that diminishes your chances of catching infections is wearing a condom.

If you are sexually active, particularly with multiple partners, you can get tested for free at the appropriate STI Clinics or GUM Clinics across the UK. There might be a wait to be seen but the check-up is quick and you can get complete cover and free condoms too.

What are the side effects?

Although doxycycline is highly effective in a low dose and unlikely to cause serious side effects, as with any other prescription drug complications may occur. The most common side effects may include diarrhoea, thrush, vomiting, heartburn, abdominal pain and a sensitivity to light.

If you are experiencing diarrhoea, it advised to steer clear of using diarrhoea tablets as these could make the side effect worse. These lighter side effects shouldn't be a cause for concern, but if they persist or you start to develop anything more serious, you should seek medical advice straight away.

Although this is rare, Doxycycline may cause intracranial hypertension in women who are overweight, childbearing age and there is a family history of the illness. Symptoms of intracranial hypertension include changes to your vision including blurred vision and headaches. If you're experiencing this, visit your doctor.

An allergic reaction to Doxycycline needs prompt medical attention. Symptoms include a fever, hives, rash, joint pain and fatigue. This could also be a result of the body combatting the medication; a condition called autoimmune syndrome.

Women should also be aware that Doxycycline can reduce the effectiveness of oral contraceptives, especially if it contains oestrogen. Please check with your doctor and use additional protection such as condoms for the remainder of that cycle.

If you are taking doxycycline to treat Chlamydia and you are experiencing symptoms of an infection which have not improved by the time you have finished your course of treatment, consult your doctor or a sexual health clinic immediately.

Ordering online

You can order Doxycycline online at 121doc. To ensure that our doctors have all the right information regarding your current health and the destination you are travelling to, we ask all our patients to complete an online consultation form. This form will be checked and if approved, a prescription for your travel treatment will be sent to our pharmacy from where your order will be sent directly to you. All orders with 121doc include a free consultation and next day delivery.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.


What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
Is the price all-inclusive?
Can I place more than one order at a time?
What are my delivery options?
Is it safe to buy prescription medication online?
How do I know which treatment is best for me?
Is this service discreet?
What is included in the online consultation?

Our consultations include general questions about your health (e.g. blood pressure levels, current and past conditions), as well as specific questions related to your selected treatment. We will also request relevant personal information to complete payment and delivery.

All questions are necessary, and your answers and details will not be shared with any third-parties. Only our doctors have access to your medical information.

Will a doctor review my consultation?

It is a legal and medical requirement that a doctor first reviews all completed consultations. We have a team of in-house doctors and specialists who will ensure your selected treatment is safe for your use. All information is stored securely and confidentially.

Please note, we do not guarantee that our doctors will approve treatment.

What happens after I submit my order?

Your consultation will be sent directly to our medical team, where it will be reviewed by one of our doctors.

If your chosen treatment is deemed suitable for your use, they will issue a prescription. Your prescription is then forwarded to our pharmacy, where your medication will be dispensed and dispatched for courier delivery.

Is the price all-inclusive?

Yes. All 121doc orders include a medical consultation, a prescription and next-day delivery. There are no additional costs. We believe in providing a safe and easy-to-use service.

Can I place more than one order at a time?

Yes. However, certain medications may negatively interact with each other. Our doctors may not approve your order on this basis.

You can place multiple items in one basket, and complete a consultation for all.

If you wish to place a second order for a different medication, you will have to complete a separate consultation.

What are my delivery options?

We offer several delivery options:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not available, a friend or relative can sign in your place.

None of these options will incur an additional charge.

Is it safe to buy prescription medication online?

To ensure you are purchasing from a reputable company, you should look to see their country’s regulatory bodies verify them.

In the UK, this is the Care Quality Commission (CQC) and the Medicines and Healthcare products Regulatory Agency (MHRA).Certificates can be viewed here.

How do I know which treatment is best for me?

Some treatments also offer the 'Advise Me' function. You will be asked questions about your lifestyle and needs, plus medical questions. You will then be presented with the advice of our doctors.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also regularly inspected by various UK regulatory agencies, such as the Information Commissioner's Office (ICO).

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

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How does it work?

Select Select your treatment and complete our online consultation.
Free consultation


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!