Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How Melatonin works

Melatonin is a hormone that is naturally produced by the body and helps dictate sleeping patterns. When it's night-time the body produces more of this hormone than during the day, however travelling to a different time zone can throw this rhythm off. In this instance, Melatonin may be required to ease the body into a new sleeping pattern, allowing you to get on with your routine as normal.

Who can take Melatonin?

Melatonin is available on prescription and, like all prescription medications, may not be suitable for everybody to take. For example, those with kidney or liver problems or who are taking oral medicines for psoriasis should seek alternative treatment.

If you are ordering online from 121doc, you should ensure that you answer our consultation as thoroughly as possible, listing all the information regarding your current and past medical conditions.

Please note, this treatment is currently being prescribed off-label.

How to take this medication

Melatonin is normally prescribed as a treatment for insomnia, for which the duration is three weeks. If prescribed for jet lag it should be used as and when it is needed, and only once you have arrived at your destination.

One tablet should be taken whole with a glass of water, one to two hours before your bedtime. It's not advised to take Melatonin when drinking alcohol as this may inhibit how it works.

Side effects

One of the advantages of Melatonin is that side effects are not very common, however certain individuals may experience irritability, anxiety and dry mouth. These effects are not usually serious and should only be temporary. Nevertheless, if you feel side effects persist or notice anything more serious, you should seek immediate medical attention.

How to buy Melatonin online

Before ordering Melatonin we ask all our patients to complete a quick and confidential consultation. Once reviewed and approved by one of our doctors, we will issue a prescription and deliver the treatment to an address of your choice.

Other treatments that might interest you


Minimise the unpleasant symptoms of motion sickness.

  • Reduces headaches, sweating and vomiting
  • Works in 20 minutes


Travelling abroad? Get preventative medications to safeguard you.

  • Protects against malaria
  • One dose daily
  • Free next-day delivery

What others say about us

4.6 score - 6360 Reviews

How does it work?

Select Select your treatment and complete our online consultation.
Free consultation


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!