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Combined Pill | Active ingredient(s): Ethinylestradiol & Norgestimate | Manufacturer: Janseen


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  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How does Cilest work?

Cilest is a combined oral contraceptive pill which contains synthetic versions of both oestrogen and progestogen, in the form of norgestimate and ethinylestradiol. The changing levels of these hormones govern the female reproductive cycle, preparing the body for conception. By manipulating the levels of hormones in the blood stream, Cilest significantly lowers the likelihood of an egg being released (ovulation) and makes it almost impossible for any eggs to develop.

The two active ingredients in Cilest work to prevent pregnancy in three different ways. Firstly, it tricks the body into thinking an egg has already been released by the ovaries. Secondly, this treatment alters the womb lining to prevent an egg from being able to implant there and develop. Thirdly, it causes a slight thickening of the cervical mucus, which helps stop sperm from entering the womb. The three stage approach that Cilest employs is the most effective method at preventing pregnancy currently available.

What are the benefits?

The key benefit of Cilest is that it offers 99.7% protection against pregnancy, meaning you will have less than a one in a hundred chance of becoming pregnant. Cilest is one of most effective female contraceptive medications available. The generic version Cilique contains the same active ingredients and dosages and works in exactly the same way as Cilest.

Aside from effective contraception, Cilest/Cilique can also help to reduce the symptoms of hormonally caused acne and alleviate endometriosis. This condition causes the womb lining to grow on areas outside of the womb, which can cause severe pain in the lower abdomen, back and pelvis. Problems such as premenstrual syndrome and period pains might also be improved with the usage of Cilest.

Who can use Cilest?

Cilest can be used by women who want to prevent pregnancy using a hormonal contraceptive method. You are able to continue taking Cilest up until menopause, however you should consult with your doctor if you are 50 and have not yet reached menopause. At that point, your doctor can determine whether Cilest is still the right option for you or whether you should move to a different contraceptive method.

Cilest includes synthetic forms of both oestrogen and progestogen, so it should not be used by women who are pregnant or currently breastfeeding. You may also not want to use a combined contraceptive like Cilest or Cilique if you are particularly sensitive to oestrogen. There are certain conditions and medications that may impact your suitability for this treatment. You should include any medications that you are currently taking on the medical consultation when placing your order. Also, it is important to include any medical conditions you may be suffering from, particularly cardiovascular and lung conditions.

How to use it?

Cilest (Cilique) should be taken for a 21 day period, which is followed by a seven day break before you begin the treatment course again. The medication will provide full cover against pregnancy during this rest period although a withdrawal bleed similar to a period may occur. Once the seven day rest period has finished, you should start your next pack of pack of Cilest, even if you are still experiencing the withdrawal bleed.

Ideally, you should start taking this medication on the first day of your period. If you start the treatment between day two and day five of your period, you will need to use a barrier contraceptive method for seven days after the first dose. As with all contraceptive medications, you must ensure that you use Cilest as per the instructions. Each tablet can be taken with or without food. If you do miss taking a tablet at the correct time, you should refer to the patient leaflet for instructions.

Are there any side effects?

As with all prescription medication, there is a risks of encountering unwanted side effects during treatment with Cilest or Cilique. Most commonly reported side effects of the contraceptive include nausea, vomiting, headaches, breast tenderness, and weight fluctuations.

These symptoms are usually light in nature and temporary. The risk of side effects is especially high at the beginning of the treatment while the body adjusts the hormone levels to the medication, but subsides once the adjustment is completed. You should consult with your doctor if you experience any long-lasting side effect or issues which cause you significant discomfort.

How to buy Cilest online?

We provide Cilest (Cilique) in convenient pack sizes for 3 or 6 months of treatment. Once you have selected the quantity that you need, you are ready to begin the ordering process. The first stage consists of some online medical questions, which our doctors will use to check your suitability for the medication. If the doctor agrees that Cilest is the correct contraceptive treatment for you, a prescription will be sent to our pharmacist for same day dispatch.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.


What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
Is the price all-inclusive?
Can I place more than one order at a time?
What are my delivery options?
Is it safe to buy prescription medication online?
How do I know which treatment is best for me?
Is this service discreet?
What is included in the online consultation?

Our consultations include general questions about your health (e.g. blood pressure levels, current and past conditions), as well as specific questions related to your selected treatment. We will also request relevant personal information to complete payment and delivery.

All questions are necessary, and your answers and details will not be shared with any third-parties. Only our doctors have access to your medical information.

Will a doctor review my consultation?

It is a legal and medical requirement that a doctor first reviews all completed consultations. We have a team of in-house doctors and specialists who will ensure your selected treatment is safe for your use. All information is stored securely and confidentially.

Please note, we do not guarantee that our doctors will approve treatment.

What happens after I submit my order?

Your consultation will be sent directly to our medical team, where it will be reviewed by one of our doctors.

If your chosen treatment is deemed suitable for your use, they will issue a prescription. Your prescription is then forwarded to our pharmacy, where your medication will be dispensed and dispatched for courier delivery.

Is the price all-inclusive?

Yes. All 121doc orders include a medical consultation, a prescription and next-day delivery. There are no additional costs. We believe in providing a safe and easy-to-use service.

Can I place more than one order at a time?

Yes. However, certain medications may negatively interact with each other. Our doctors may not approve your order on this basis.

You can place multiple items in one basket, and complete a consultation for all.

If you wish to place a second order for a different medication, you will have to complete a separate consultation.

What are my delivery options?

We offer several delivery options:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not available, a friend or relative can sign in your place.

None of these options will incur an additional charge.

Is it safe to buy prescription medication online?

To ensure you are purchasing from a reputable company, you should look to see their country’s regulatory bodies verify them.

In the UK, this is the Care Quality Commission (CQC) and the Medicines and Healthcare products Regulatory Agency (MHRA).Certificates can be viewed here.

How do I know which treatment is best for me?

Some treatments also offer the 'Advise Me' function. You will be asked questions about your lifestyle and needs, plus medical questions. You will then be presented with the advice of our doctors.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also regularly inspected by various UK regulatory agencies, such as the Information Commissioner's Office (ICO).

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

What others say about us

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How does it work?

Select Select your treatment and complete our online consultation.
Free consultation


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!