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Rosacea | Active ingredient(s): Doxycycline | Manufacturer: GALDERMA

Take one capsule daily.

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  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included


Efracea is a type of oral medication that commonly comes in the form of capsules that is taken to treat Rosacea. Inside this medication is a low dose of an active substance known as Doxycycline. Doctors commonly prescribe Efracea to reduce symptoms such as inflammation, pimples, spots, veins, and red bumps that occur on the skin and face due to Rosacea.

How it works

Rosacea tends to be a lifelong skin condition that fluctuates between being inactive and active. To help deal with this long term condition, the low dose of Doxycycline inside the capsule is released slowly, causing a steady anti-inflammatory effect on the body. Doxycycline helps calm the skin, reduce redness and irritation on the face and skin.

Dosage information

You should only take Efracea if you’ve been prescribed it by your doctor. Most doses come in 40mg modified release capsules and users are advised to take each morning. Always stick to the prescription guidelines given by your general practitioner. If you take more than the recommended dose, consult advice from your doctor immediately.

How to use

You should take this medication on an empty stomach with a full glass of water, no food. Preferably you should take it one hour before eating or two hours following your meal. You should never crush the tablets and avoid taking them within a close time frame of milk or antacids, as this can decrease the effectiveness of the medication.

Side effects

Consult your doctor immediately if you experience any of the following side effects when taking Efracea:

  • dizziness
  • vision problems
  • allergic reactions
  • little or no urination
  • difficulty swallowing
  • severe weakness
  • swollen glands

Common side effects

If you take Efracea, you may be prone to experience some common side effects:

  • sinus headaches
  • fungal infections
  • diarrhea
  • anxiety
  • dry mouth
  • skin rash
  • upset stomach
  • vaginal itching
  • discharge

These side effects may only occur in a select number of users; however, if you do experience them, they tend to be minor and not long-term. If you notice they persist while taking, speak to your doctor for advice.

Before beginning your Efracea treatment, you should read the patient leaflet inside the medication box. Doing this will enable you to learn more about the potential side effects of this medication and will allow you to seek medical advice when required.


Taking Efracea alongside other medications or specific foods may reduce its effectiveness or trigger adverse reactions. Therefore, do not take Efracea and consult with your doctor first if you are taking the following:

  • Medication for acne, in particular isotretinoin. It can increase your risk of pressure on the brain.
  • Treatment for heartburn or ulcers.
  • Antibiotics can limit the effectiveness.
  • Sleeping pills and seizure medication. It can decrease the amount of time Efracea remains in your system.
  • Diabetes or blood-thinning medication. Your doctor may have to change your dose.
  • For women who are taking the contraceptive pill, its effectiveness might be reduced.

If you take any products, supplements, or medication containing calcium, aluminum, sucralfate, iron, magnesium , bismuth, activated charcoal, and cholestyramine, speak to your doctor first. Taking these at the same time may reduce the effectiveness of Efracea.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.


What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
Is the price all-inclusive?
Can I place more than one order at a time?
What are my delivery options?
Is it safe to buy prescription medication online?
How do I know which treatment is best for me?
Is this service discreet?
What is included in the online consultation?

Our consultations include general questions about your health (e.g. blood pressure levels, current and past conditions), as well as specific questions related to your selected treatment. We will also request relevant personal information to complete payment and delivery.

All questions are necessary, and your answers and details will not be shared with any third-parties. Only our doctors have access to your medical information.

Will a doctor review my consultation?

It is a legal and medical requirement that a doctor first reviews all completed consultations. We have a team of in-house doctors and specialists who will ensure your selected treatment is safe for your use. All information is stored securely and confidentially.

Please note, we do not guarantee that our doctors will approve treatment.

What happens after I submit my order?

Your consultation will be sent directly to our medical team, where it will be reviewed by one of our doctors.

If your chosen treatment is deemed suitable for your use, they will issue a prescription. Your prescription is then forwarded to our pharmacy, where your medication will be dispensed and dispatched for courier delivery.

Is the price all-inclusive?

Yes. All 121doc orders include a medical consultation, a prescription and next-day delivery. There are no additional costs. We believe in providing a safe and easy-to-use service.

Can I place more than one order at a time?

Yes. However, certain medications may negatively interact with each other. Our doctors may not approve your order on this basis.

You can place multiple items in one basket, and complete a consultation for all.

If you wish to place a second order for a different medication, you will have to complete a separate consultation.

What are my delivery options?

We offer several delivery options:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not available, a friend or relative can sign in your place.

None of these options will incur an additional charge.

Is it safe to buy prescription medication online?

To ensure you are purchasing from a reputable company, you should look to see their country’s regulatory bodies verify them.

In the UK, this is the Care Quality Commission (CQC) and the Medicines and Healthcare products Regulatory Agency (MHRA).Certificates can be viewed here.

How do I know which treatment is best for me?

Some treatments also offer the 'Advise Me' function. You will be asked questions about your lifestyle and needs, plus medical questions. You will then be presented with the advice of our doctors.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also regularly inspected by various UK regulatory agencies, such as the Information Commissioner's Office (ICO).

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

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How does it work?

Select Select your treatment and complete our online consultation.
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Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!