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Spedra

Erectile Dysfunction|Active ingredient(s): Avanafil|Manufacturer: Various

A happy man sitting on the sofa about to take a tablet

The World's Fastest ED Treatment — Ready When You Are

  • Stronger erections in as little as 15 minutes
  • Effective results for up to 4-5 hours
  • As-needed dosing
  • Trusted by millions worldwide
  • Available in 50 mg, 100 mg, and 200 mg doses

How to take

A young couple holding hands at a romantic dinner

Set the stage

Create a comfortable environment and prepare for intimacy.

A close up of a man’s hand holding two yellow tablets

Choose your moment

Take your tablet 15-30 minutes before you plan to have sex.

A young couple being intimate in bed

Make it count

Be present, relax, and let Spedra reignite your spark.

What others say about Spedra

Trustpilot review
57 reviews with score 4.6

Quality healthcare
made easy

Price is all-inclusive.
Consultation is included.
Prescription is included.

Free shipping.
UK: Free next-day delivery.
Discreet packaging.

Licensed doctors.
Registered pharmacies.
Certified online pharmacy.

Spedra

What is Spedra?

Spedra is the fastest erectile dysfunction treatment on the market, helping millions of men around the world achieve stronger erections in as little as 15 minutes. It is a branded version of the drug Avanafil.

Taken only when needed, Spedra should be used 15–30 minutes before sexual activity, offering a discreet and reliable way to restore sexual confidence.

Spedra vs Viagra: which is better?

Spedra and Viagra are both effective ED treatment options with their own unique benefits. Consider the following when choosing your erectile dysfunction medication:

  • Why choose Spedra?
    • Spedra is the fastest-acting ED treatment on the market, working in as little as 15-30 minutes and lasting for 4-5 hours. Choose Spedra if you value spontaneity and want fast results.
  • Why choose Viagra?
    • Viagra is a well-established ED treatment that works for up to 4-6 hours. Choose Viagra if you prefer a trusted option with a longer window of opportunity.

Think Viagra may suit your needs better? Explore Viagra tablets here.

How does Spedra work?

Spedra works by widening blood vessels and increasing blood flow to the genitals, making it easier to get and maintain an erection.

It achieves this through its active ingredient: avanafil. Avanafil blocks an enzyme in the body called PDE5, thus allowing blood to flow more naturally and causing harder, more reliable erections. Contrary to popular belief, ED treatments like Spedra only work when you’re sexually aroused, so you should only get an erection when you need it.

How effective is Spedra?

Spedra has been proven in clinical trials to be a safe and effective ED medication, improving the sex lives of many men who trust it as their treatment of choice.

One such trial found the following:

  • Effectiveness:
    • Spedra: ~66% of sexual encounters were successful
    • Placebo: ~25% of sexual encounters were successful
  • Safety:
    • Less than 2% of Avanafil and placebo recipients discontinued treatment because of adverse events.

How long does Spedra take to work?

Spedra is the fastest-acting ED treatment available—working in as little as 15 minutes.

It can work this quickly, but for some men it may take up to half an hour, especially if you have eaten beforehand. Peak effects are typically felt within 30-60 minutes.

How long does Spedra last?

Spedra typically lasts for 4-5 hours. You can have sex multiple times during this period without the medicine losing effectiveness.

If the effects last longer than this or you experience an erection that won't go down (priapism), seek immediate medical help.

Who can take Spedra?

Spedra can only be prescribed to men over 18 years old who experience erectile dysfunction.

Do not take Spedra if you have:

  • an allergy to avanafil or any other ingredient found in this medicine
  • a serious heart problem
  • had a stroke or heart attack within the last 6 months
  • low or high blood pressure
  • chest pain
  • a serious kidney or liver problem
  • an inherited eye disorder

For more information, consult the patient information leaflet.

What dose should I take?

There are three doses of Spedra available: 50 mg, 100 mg, and 200 mg. Consult this table to see which one is right for you:

Dose When it’s prescribed Who it’s prescribed for
100 mg Recommended starting dose Most healthy men
50 mg If 100 mg is too strong At-risk groups (over 65, liver or kidney problems, etc.)
200 mg If 100 mg is too weak Men who don’t respond to 100 mg and experience no side effects

Are there any side effects?

Most people won’t experience side effects from Spedra, but they can happen. The most common Spedra side effects include:

  • headache
  • flushing
  • stuffy nose
  • dizziness
  • feeling tired
  • sinus blockage
  • back pain
  • faster heartbeat
  • indigestion
  • blurry vision

For a full list of side effects, consult the patient information leaflet.

Can I get Spedra without a prescription?

Safety is our number one priority at 121doc. For this reason, our doctors will only prescribe Spedra if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects
Medical review byDr. Caroline FontanaLast review 14 October 2025
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Spedra Overview

Type of medicine PDE5 inhibitor
Used for Erectile dysfunction
Active ingredient Avanafil
Works by Relaxing blood vessels and increasing blood flow to the penis when sexually stimulated
Effective within 15-30 minutes
Available as Tablets
Available dosage(s) 50 mg, 100 mg, 200 mg
Usage instructions Take one tablet with water 15-30 minutes before you plan to have sex. Do not exceed one tablet per day
Packaging Blister packs
Manufacturer Menarini

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

Comparison

 Pack of 4 Viagra tablets, each containing 25mg of sildenafil and coated in a thin layer of filmCialis® 10mg tadalafil film-coated 4 tabletsCialis® 5mg tadalafil 28 film-coated tablets
 Overview
OverviewMost popularWeekend pillDaily pill
 Active ingredient(s)
Active ingredient(s)SildenafilTadalafilTadalafil
 Works in
Works in30-60 min30-60 min3-5 days
 Lasts
Lasts4 hours36 hoursContinuously
 Features
FeaturesFast-actingLong-lastingSpontaneous intercourse
 Side effects
Side effectsUsually mildUsually mildLow risk
 Alcohol
AlcoholCautionCautionCaution
 How to take
How to take1 pill max a day1 pill max a dayDaily tablet
 Price
Price£39.99£54.99£99.99
 
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Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
Prescribe Our doctors review your order.
Free prescription

Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat
Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off

Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!