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Manufactured by Xenical capsule with Roche logo


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120 patient review(s)

Xenical (orlistat) is a weight loss medication that blocks the absorption of up to 30% of the fat from your daily food intake. The prescription medication can support weight loss in combination with a diet and exercise plan. You can buy Xenical online at 121doc by selecting your quantity requirements and answering a few online medical questions. We offer fast and discreet dispatch options, with all medications being eligible for next day delivery.

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How does Xenical work?

The active ingredient in Xenical tablets is orlistat, which works to reduce the amount of fat that the body absorbs from meals. Xenical can help reduce weight when taken in combination with a healthy diet and effective exercise regime.

Orlistat is a lipase inhibitor, it works by altering the way some of the enzymes in the digestive system work, specifically the two that help break down fats. Fat molecules are generally too large to be absorbed directly into the bloodstream and need to be broken down before this can happen. By inhibiting the enzymes that usually perform this task, Xenical can significantly reduce the amount of fat that the body is able to absorb. The reduction can be up to 30%, which over time will result in significant weight loss if used as recommended. The excess fat is passed through the system and excreted in the faeces.

What are the benefits of Xenical?

Xenical is a clinically proven weight loss medication which can aid weight loss if combined with a healthier diet. It is important to monitor the weight loss achieved through the treatment with Xenical closely. The doctor will set a target before your first course of treatment, which normally consists of a 5% weight loss compared to your starting weight (this can go down to 3% in patients with diabetes). If you fail to reach this goal after a 12-week treatment with Xenical, you will be recommended to seek alternative treatment options to minimise the risk of side effects.

Who can buy Xenical online?

Orlistat can be used by people who are over the age of 18 and who have a body mass index (BMI) of 30 or above. If your BMI is 28-30, but you are suffering from underlying health complications that are exacerbated by your weight, the doctor may consider you for this treatment. You are not suitable for the treatment with Xenical if you are breastfeeding, pregnant or suffer from cholestasis, which is a condition that results in decreased bile flow. If any of these apply to you, please speak to your doctor in order to find a more appropriate weight loss treatment.

How do you use Xenical?

Xenical comes in a 120mg tablet that is taken three times a day. You should take this with meals, although you can take it up to one hour after you have eaten. You should ensure that your fat intake is split evenly between your meals to ensure this medication works correctly. You should not use Xenical if the meal that you have eaten does not contain any fat. Equally, please avoid a diet especially rich in fat when taking Xenical as this may lead to an increased risk of unpleasant side effects.

The normal course of treatment with Xenical is 12 weeks, after which the doctor will reassess your suitability for the treatment. If you have lost at least 5% of your starting weight and haven't suffered from a lot of side effects, treatments will normally be continued with another 12-week course. If you have lost less than 5% of your starting weight, a treatment continuation may not be recommended. Please speak to your doctor about alternative treatment options should a repeat prescription be denied.

Are there any side effects?

As with all prescription medication, this treatment may produce some side effects in a small number of users. These are more likely to occur within the digestive tract, as this is the localised area where orlistat takes effect. You may experience more bowel movements and an oily discharge, especially if you are eating meals that have a high fat content. Further side effects of orlistat can include:

  • nausea
  • abdominal pain
  • headaches
  • bloating, flatulance (wind)
  • low blood sugar levels
  • tooth or gum disorder
  • irregularity of the menstrual cycle

If you experience any continued or serious side effects, you should speak to your doctor or contact our dedicated customer support team.

What are contraindications and interactions of Xenical?

You should not take Xenical if you are allergic to Orlistat or any of its ingredients. If you are pregnant or breastfeeding a treatment with Xenical is strictly prohibited. People with chronic malabsorption syndrome or liver disorders should refrain from taking Xenical.

You should always mention any other medications you are currently taking during the consultation as dangerous drug interactions may occur. The following medications are known to interact with Xenical:

  • Anticoagulant drugs (e.g. warfarin)
  • Ciclosporin
  • Iodine salts and/or levothyroxine
  • Amiodarone
  • Acarbose (as diabetes type II treatment)
  • antiepileptic drugs

How to buy Xenical online?

You can buy Xenical online at 121doc without a face-to-face doctor's appointment or previous prescription. Part of the ordering process is an online medical questionnaire, which our doctors will use to check whether this is a suitable treatment for you. If our doctors approve the order, your treatment will be dispensed from our UK registered pharmacy. We offer the next day delivery to all of our customers at no extra cost.

Last updated: 04/06/2019

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