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Weight Loss | Active ingredient(s): Orlistat | Manufacturer: Cheplapharm

Take three capsules a day, during, or within one hour after, each meal.

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  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How does Xenical work?

The active ingredient in Xenical tablets is orlistat, which works to reduce the amount of fat that the body absorbs from meals. Xenical can help reduce weight when taken in combination with a healthy diet and effective exercise regime.

Orlistat is a lipase inhibitor, it works by altering the way some of the enzymes in the digestive system work, specifically the two that help break down fats. Fat molecules are generally too large to be absorbed directly into the bloodstream and need to be broken down before this can happen. By inhibiting the enzymes that usually perform this task, Xenical can significantly reduce the amount of fat that the body is able to absorb. The reduction can be up to 30%, which over time will result in significant weight loss if used as recommended. The excess fat is passed through the system and excreted in the faeces.

What are the benefits of Xenical?

Xenical is a clinically proven weight loss medication which can aid weight loss if combined with a healthier diet. It is important to monitor the weight loss achieved through the treatment with Xenical closely. The doctor will set a target before your first course of treatment, which normally consists of a 5% weight loss compared to your starting weight (this can go down to 3% in patients with diabetes). If you fail to reach this goal after a 12-week treatment with Xenical, you will be recommended to seek alternative treatment options to minimise the risk of side effects.

Who can buy Xenical online?

Orlistat can be used by people who are over the age of 18 and who have a body mass index (BMI) of 30 or above. If your BMI is 28-30, but you are suffering from underlying health complications that are exacerbated by your weight, the doctor may consider you for this treatment. You are not suitable for the treatment with Xenical if you are breastfeeding, pregnant or suffer from cholestasis, which is a condition that results in decreased bile flow. If any of these apply to you, please speak to your doctor in order to find a more appropriate weight loss treatment.

How do you use Xenical?

Xenical comes in a 120mg tablet that is taken three times a day. You should take this with meals, although you can take it up to one hour after you have eaten. You should ensure that your fat intake is split evenly between your meals to ensure this medication works correctly. You should not use Xenical if the meal that you have eaten does not contain any fat. Equally, please avoid a diet especially rich in fat when taking Xenical as this may lead to an increased risk of unpleasant side effects.

The normal course of treatment with Xenical is 12 weeks, after which the doctor will reassess your suitability for the treatment. If you have lost at least 5% of your starting weight and haven't suffered from a lot of side effects, treatments will normally be continued with another 12-week course. If you have lost less than 5% of your starting weight, a treatment continuation may not be recommended. Please speak to your doctor about alternative treatment options should a repeat prescription be denied.

Are there any side effects?

As with all prescription medication, this treatment may produce some side effects in a small number of users. These are more likely to occur within the digestive tract, as this is the localised area where orlistat takes effect. You may experience more bowel movements and an oily discharge, especially if you are eating meals that have a high fat content. Further side effects of orlistat can include:

  • nausea
  • abdominal pain
  • headaches
  • bloating, flatulance (wind)
  • low blood sugar levels
  • tooth or gum disorder
  • irregularity of the menstrual cycle

If you experience any continued or serious side effects, you should speak to your doctor or contact our dedicated customer service team.

What are contraindications and interactions of Xenical?

You should not take Xenical if you are allergic to Orlistat or any of its ingredients. If you are pregnant or breastfeeding a treatment with Xenical is strictly prohibited. People with chronic malabsorption syndrome or liver disorders should refrain from taking Xenical.

You should always mention any other medications you are currently taking during the consultation as dangerous drug interactions may occur. The following medications are known to interact with Xenical:

  • Anticoagulant drugs (e.g. warfarin)
  • Ciclosporin
  • Iodine salts and/or levothyroxine
  • Amiodarone
  • Acarbose (as diabetes type II treatment)
  • antiepileptic drugs
  • oral contraceptives (e.g. the combined pill or mini-pill)

How to buy Xenical online?

You can buy Xenical online at 121doc without a face-to-face doctor's appointment or previous prescription. Part of the ordering process is an online medical questionnaire, which our doctors will use to check whether this is a suitable treatment for you. If our doctors approve the order, your treatment will be dispensed from our UK registered pharmacy. We offer the next day delivery to all of our customers at no extra cost.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.


What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
Is the price all-inclusive?
Can I place more than one order at a time?
What are my delivery options?
Is it safe to buy prescription medication online?
How do I know which treatment is best for me?
Is this service discreet?
What is included in the online consultation?

Our consultations include general questions about your health (e.g. blood pressure levels, current and past conditions), as well as specific questions related to your selected treatment. We will also request relevant personal information to complete payment and delivery.

All questions are necessary, and your answers and details will not be shared with any third-parties. Only our doctors have access to your medical information.

Will a doctor review my consultation?

It is a legal and medical requirement that a doctor first reviews all completed consultations. We have a team of in-house doctors and specialists who will ensure your selected treatment is safe for your use. All information is stored securely and confidentially.

Please note, we do not guarantee that our doctors will approve treatment.

What happens after I submit my order?

Your consultation will be sent directly to our medical team, where it will be reviewed by one of our doctors.

If your chosen treatment is deemed suitable for your use, they will issue a prescription. Your prescription is then forwarded to our pharmacy, where your medication will be dispensed and dispatched for courier delivery.

Is the price all-inclusive?

Yes. All 121doc orders include a medical consultation, a prescription and next-day delivery. There are no additional costs. We believe in providing a safe and easy-to-use service.

Can I place more than one order at a time?

Yes. However, certain medications may negatively interact with each other. Our doctors may not approve your order on this basis.

You can place multiple items in one basket, and complete a consultation for all.

If you wish to place a second order for a different medication, you will have to complete a separate consultation.

What are my delivery options?

We offer several delivery options:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not available, a friend or relative can sign in your place.

None of these options will incur an additional charge.

Is it safe to buy prescription medication online?

To ensure you are purchasing from a reputable company, you should look to see their country’s regulatory bodies verify them.

In the UK, this is the Care Quality Commission (CQC) and the Medicines and Healthcare products Regulatory Agency (MHRA).Certificates can be viewed here.

How do I know which treatment is best for me?

Some treatments also offer the 'Advise Me' function. You will be asked questions about your lifestyle and needs, plus medical questions. You will then be presented with the advice of our doctors.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also regularly inspected by various UK regulatory agencies, such as the Information Commissioner's Office (ICO).

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

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How does it work?

Select Select your treatment and complete our online consultation.
Free consultation


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!