Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How Evorel patches work

Evorel is a transdermal patch that supplies the body with oestrogen via the skin. This compensates for the loss of hormones as a result of menopause and therefore aims to stabilise the body's internal hormonal balance, so it's as close as possible to how it was before menopause. By doing this the patches help to naturally avoid symptoms such as hot flushes, night sweats, vaginal dryness and vaginal itching.

Who the patches are for

These patches are intended for women who have had a hysterectomy and who are experiencing the symptoms associated with menopause. However, women who have not had a hysterectomy may also use this treatment alongside clinical progestogen.

You may not have been prescribed this treatment if you are allergic or sensitive to oestrogen, you have a history of oestrogen-dependent cancer or you are prone to blood clotting or other similar circulatory problems.

Evorel patch doses

It is available in four different doses, but you'll likely be started off on the smallest dose first. The available doses include 25 mcg (releases 25 micrograms of estradiol via the skin over a 24 hour period), 50mcg (releases 50 micrograms), 75mcg (releases 75 micrograms) and 100mcg (releases 100 micrograms).

Evorel Conti or Evorel Sequi, which contain different doses as well as progestogen, are possible alternatives to the patch.

The side effects

Just like any prescription treatment, HRT can cause side effects, although when you are prescribed an HRT medication, you'll be monitored carefully by your doctor to make sure that you are still getting the best from your treatment. Some of the most common side effects include irritation of the application area, breast tenderness, acne, changes in mood, heavy periods, headaches or insomnia. These side effects are mostly a sign that the body is adjusting to the new hormones, but if they persist or you experience anything more serious, you should contact your doctor.

Buying online

Evorel Patches are available to order safely online at 121doc. We ask all our patients to complete a confidential consultation form so that our doctor can make sure that you can use this medication safely. If for any reason you cannot use this treatment please see our range of HRT treatments. our doctor will also only consider prescribing this treatment if your doctor has already recommended it to you. If a prescription is approved it will be passed to our pharmacy, from where your patches will be shipped with free next day delivery.


Elleste Solo MXPremarinEvorel
Overview Oestrogen-only HRT patchOestrogen-only HRT tabletsOestrogen-only HRT patches
Progestogen ---
Oestrogen 40mcg, 80mcg Estradiol hemihydrate0.3mg, 0.625mg, 1.25mg Conjugated oestrogens25 mcg, 50 mcg, 75 mcg, 100 mcg Estradiol every 24h
  Active ingredient(s)
Active ingredient(s) Estradiol hemihydrateConjugated oestrogensEstradiol
  Who can take it
Who can take it If you have had a hysterectomyIf you have had a hysterectomyIf you have had a hysterectomy
Features --Alternative to tablets
  Side effects
Side effects ---
  How to take
How to take 1 patch twice weeklyDaily tablet1 patch twice weekly
  Price 3 month course
Price 3 month course £39.99£26.99£34.99
View treatmentView treatmentView treatment

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How does it work?

Select Select your treatment


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Redeem your prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!