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Seretide

Asthma|Active ingredient(s): Fluticasone & Salmeterol|Manufacturer: GSK

A young woman using a purple asthma inhaler

Long-term asthma management with Seretide

  • Effective daily combination treatment for asthma and COPD
  • Prevents flare-ups by reducing airway inflammation and opening up the airways
  • Available as an aerosol (Evohaler) and a dry powder inhaler (Accuhaler)
  • Can be used alongside a reliever inhaler such as Ventolin
  • Available in 50, 100, 125 and 250 mcg formulations

How to use

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Use daily at the same time

Use your inhaler around the same time every day. The typical dose is 1-2 puffs in the morning and evening.

Young man holding a purple inhaler

Inhale your dose

Your inhalation technique depends on your inhaler: either press down on the canister as you breathe in (Evohaler) or just take a deep, quick breath (Accuhaler) to deliver your dose.

Two identical arrows forming a circle

Repeat if needed

If you have been told to take 2 doses, repeat these steps. Rinse your mouth with water after each dose to reduce the risk of side effects, like thrush.

What others say about Seretide

Trustpilot review
5 reviews with score 4.8

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Seretide

What is Seretide?

Seretide is a combination inhaler that contains two active ingredients: fluticasone propionate and salmeterol. It can be used to treat asthma and COPD. It is a preventer inhaler, meaning it helps keep symptoms in control and prevents flare-ups.

Seretide is available in two forms: a 50 mcg aerosol (Evohaler) and a 100 mcg dry powder (Accuhaler) inhaler.

How does Seretide work?

The combination of fluticasone and salmeterol offers effective symptom management for asthma and COPD.

  • Fluticasone (a corticosteroid) helps reduce swelling and irritation in the airways, which helps keep flare-ups at bay and prevents asthma attacks.
  • Salmeterol (a long-acting beta2-agonist) works by relaxing the muscles in the airways, allowing them to stay open. This helps you breathe easier.

Together these active ingredients work to improve breathing and lung function and reduce the frequency of symptoms in the long-term.

How effective is Seretide?

Fluticasone and salmeterol combination inhalers have been widely studied in clinical trials and have been proven effective in the treatment of moderate to severe asthma and COPD.

A 12-week study observed patients who switched from their previous inhaler to a fluticasone and salmeterol inhaler. The study results showed that:

  • After 12 weeks of treatment, the participants’ asthma control scores had improved significantly: 83.6% of patients had well-controlled asthma, an over 70% improvement from the baseline
  • Treatment significantly improved lung function in patients with asthma or COPD
  • Patients found the inhalers easy to use and incorporate into everyday life

Who can use Seretide?

To be prescribed Symbicort from 121doc, you must be over the age of 18 and have been diagnosed with moderate to severe asthma or COPD that cannot be controlled with a steroid-only inhaler alone.

How do I use Seretide?

You need to use Seretide correctly for it to work effectively. You should also follow the asthma management plan as instructed by your doctor or asthma nurse.

How to use Seretide depends on the type of your inhaler. To use a Seretide Evohaler, follow the instructions below.

How to use Seretide Evohaler
how-to-use1
  1. Sit upright and shake the inhaler 4-5 times.
  2. Hold the inhaler upright with your thumb on the base.
how-to-use2
  1. Hold the Evohaler away from your mouth and breathe out as far as is comfortable - do not breathe in again until you are ready to take the medicine.
how-to-use3
  1. Place the mouthpiece gently between your teeth and close your lips. Then, as you start to breathe in, press down on the top of the canister to release a puff of the medicine.
how-to-use4
  1. Keep holding your breath and take the inhaler from your mouth. Continue holding your breath for as long as it is comfortable.
how-to-use4
  1. If you need to take another dose, wait 30 seconds and repeat these steps. When you are done, replace the cover.

To use Seretide Accuhaler, follow the steps below.

How to use Seretide Accuhaler
how-to-use1
  1. To prepare a dose, slide the lever by pushing down the thumbgrip until you hear a click.
how-to-use2
  1. Hold the Accuhaler away from your mouth and breathe out as far as is comfortable - do not breathe in again before you are ready to take the medicine.
how-to-use3
  1. Inhale deeply and steadily through the mouthpiece (not through your nose).
how-to-use4
  1. Remove the Accuhaler from your mouth and hold your breath for about 10 seconds before breathing out slowly.
how-to-use4
  1. To close the inhaler, slide the thumbgrip back towards you until you hear a click. This will reset the Accuhaler.

How long does it take for Seretide to work?

You may notice some improvement in your symptoms within a few days of starting Seretide, but it typically takes up to 1-2 weeks to experience its full benefits.

How long do I have to use Seretide for?

Seretide is intended for long-term management of asthma or COPD symptoms. Do not stop using it unless your doctor decides to prescribe you a different inhaler.

What are the side effects of Seretide?

Like all medications, Seretide inhalers can cause some side effects. However, they are generally mild and rarely serious.

Common side effects of Seretide include:

  • oral thrush
  • throat irritation and hoarseness
  • cough
  • headache
  • palpitations (fast heartbeat) or tremors
  • muscle cramps
  • joint pain

If you experience any severe or worrying side effects, such as an increase in shortness of breath after using the inhaler, or swelling of the face or mouth or other signs of an allergic reaction, seek medical attention straight away.

To read more about the potential side effects of Seretide, refer to the patient information leaflet.

Can Seretide and Ventolin be used together?

Yes. Seretide is a preventer inhaler and Ventolin (salbutamol) is a reliever. Most people are prescribed a reliever inhaler alongside their daily preventer. You only use Ventolin if your symptoms flare up suddenly.

Can I use Seretide as a reliever?

No. Seretide is intended for long-term symptom prevention, and it is not suitable for immediate symptom relief. You should always carry a reliever (rescue) inhaler, such as Ventolin, with you in case of an asthma attack.

Is fluticasone the same as Seretide?

No. Fluticasone propionate is one of the active ingredients in Seretide, alongside salmeterol. On its own, a fluticasone inhaler (such as Flixotide) can be used to treat inflammation in the airways. Fluticasone can also be used to treat nasal allergies or, topically, skin conditions like psoriasis.

Can I buy Seretide over the counter?

No, Seretide is only available with a prescription. Safety is our number one priority at 121doc. For this reason, our doctors will only prescribe this asthma treatment to you if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects
Medical review byDr. Caroline FontanaLast review 13 April 2026
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Seretide Overview

Type of medicine Preventer inhaler
Used for Asthma
Active ingredients Fluticasone propionate & salmeterol
Works by Reduces inflammation and relaxes muscles in the airways to make breathing easier
Effective within 1-2 weeks
Available as Pressurised metered dose inhaler (Evohaler)
Dry powder inhaler (Accuhaler)
Available dosages Evohaler 25 µg/50 µg
Accuhaler 50 µg/100 µg
Usage instructions Take 1-2 puffs twice a day, as instructed by your GP
Manufacturer GlaxoSmithKline
Generic available? No

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

How does it work?

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Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.

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If you know what you want, the quickest way to find a specific medication is to use the search bar here.

Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
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Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
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Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

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Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!