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Dermovate

Psoriasis|Active ingredient(s): Clobetasol|Manufacturer: GSK

Young woman applying cream to her elbow

Potent daily eczema and psoriasis treatment

  • Strong steroid treatment used for severe psoriasis and eczema.
  • Suitable when other steroids haven’t worked
  • Available as an ointment or cream
  • 4-week treatment course.
  • Thin layer applied once or twice daily

How to use

Close-up of a fingertip of cream

Apply daily

Apply a thin layer of Dermovate once or twice daily to the affected areas.

Close-up of a hand holding a pen and pointing at a date on a calendar

4-week treatment

Dermovate is only prescribed for a maximum of 4 weeks for eczema.

A woman applying a cream to her hand

Using emollient

If you also use an emollient, you should wait for Dermovate to absorb before applying it.

What others say about Dermovate

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Price is all-inclusive.
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Dermovate

What is Dermovate?

Dermovate is a topical steroid for short-term treatment of severe eczema or psoriasis manufactured by Glaxo Wellcome. Since its approval in the EU in 1993, it has helped many people treat irritation caused by eczema and other inflammatory skin conditions, such as psoriasis.

It is a highly potent steroid and is often used where other steroids have not worked, but should not be used for long periods. It is available as both a cream and an ointment.

How does Dermovate work?

Dermovate contains the active ingredient clobetasol propionate, which is a potent steroid. It works by blocking the release of chemicals that cause inflammation. This helps to control symptoms of psoriasis and eczema, including itching, irritation and dry scaly skin.

How effective is it?

Studies show that Dermovate is an effective treatment for eczema and psoriasis.

Research shows that Dermovate significantly improved the severity of eczema symptoms after 2 weeks. There was also a lower rate of symptom relapse compared to other steroids.

Similarly, research shows that Dermovate can significantly reduce scaling and redness in psoriasis cases, with 8 in 10 people achieving almost clear skin after 4 weeks of treatment and 5 in 10 after 2 weeks.

How long does it take for Dermovate to work?

Dermovate is effective within 2 weeks of treatment. However, it may take up to 4 weeks to see the full effects. You should not use it for longer than 4 weeks.

Who can use Dermovate?

Dermovate is safe to use for most people with eczema or localised psoriasis. To be prescribed Dermovate from 121doc, you need to be diagnosed with psoriasis or eczema, and be aged 18 or over. Additionally, this treatment is not recommended if you have:

  • acne
  • perioral dermatitis (spotty red rash around the mouth)
  • widespread plaque psoriasis
  • rosacea
  • untreated bacterial, fungal or viral skin conditions
  • an allergy to clobetasol propionate or any other ingredients in Dermovate cream or ointment

Women who are breastfeeding can use Dermovate, but they should not apply it to their chest to limit the risk of exposure to an infant.

How do I use Dermovate?

You apply a thin layer of Dermovate once or twice daily to the affected areas. How much you need to apply depends on the area you need to cover:

  • face and neck: 2 ½ fingertip units
  • back or front: 7 fingertip units
  • one arm: 3 fingertip units
  • both sides of one hand: 1 fingertip unit
  • one leg: 6 fingertip units
  • one foot: 2 fingertip units

Do not apply Dermovate more than directed. This will not improve your eczema quicker and may cause additional irritation.

Avoid applying it to the eyes, lips and nostrils. Do not apply to irritated, sunburnt or broken skin. You should also not apply Dermovate to the genital or anal areas.

If you use an emollient, wait for Dermovate to be absorbed into the skin before applying it. This will ensure the treatment is effective.

How long should I use Dermovate?

You should use Dermovate for no longer than 4 weeks. This is because it is a highly potent steroid, and you may be at a higher risk of side effects if taken for long periods. If your symptoms do not improve after 2 weeks, stop using it and consult your doctor or dermatologist.

Are there any side effects?

Like all prescription medicines, Dermovate may cause side effects. The most common side effects should go away on their own once your body gets used to the medicine.

Common side effects (up to 1 in 10 people):

  • burning sensation
  • pain
  • irritation
  • itching

Speak to your doctor as soon as possible if you experience any persistent or serious side effects.

For a full list of side effects, please refer to the patient information leaflet (PIL).

Is Dermovate safe?

Yes, research suggests Dermovate is a safe and clinically-proven topical steroid treatment. But if you have another medical condition or take other medication, your doctor will need to ensure it’s safe for you. Our doctors will also know whether it’s safe for you based on your medical questionnaire during the ordering process.

Can I get Dermovate without a prescription?

No, Dermovate is not available without a prescription. Our doctors will only prescribe treatment if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects

Is Dermovate stronger than Betnovate?

Yes, Dermovate is significantly stronger than Betnovate. Both are topical steroids, but Dermovate is classified as ‘very potent’ and Betnovate as ‘potent’. For this reason, Dermovate is better suited for more severe cases of psoriasis and eczema.

What is stronger, Dermovate or Eumovate?

Eumovate is a lower-potency steroid containing clobetasone butyrate and is suitable for mild to moderate eczema or dermatitis. Dermovate, on the other hand, contains a very potent steroid (clobetasol propionate) reserved for severe and resistant forms of psoriasis and eczema that have not been successfully controlled by other steroids.

What is Dermovate ointment used for?

Dermovate ointment is an oil-based, thicker and more greasy formulation. It stays on the skin longer due to its high oil content, which helps to seal in moisture. It is best for smaller areas that are extremely dry, cracked and sensitive.

What is Dermovate cream used for?

Dermovate cream is a lighter formulation that is more water-based. It absorbs faster and is potentially more suitable for applying to larger areas. It also feels less greasy, which is a texture some may prefer compared to the ointment.

Can I use Dermovate on my scalp?

No, Dermovate ointment and cream should not be used on the scalp. However, there is a form of Dermovate specifically designed for scalp problems called Dermovate Scalp Application. Consult your doctor or dermatologist for more information.

Can I use Dermovate for lichen sclerosus?

Yes, Dermovate can be prescribed for lichen sclerosus, a chronic skin condition that affects the skin around the vulva and anus in women. However, it is only prescribed online for eczema at 121doc.

Do not apply Dermovate to these areas without consulting your doctor first. If you think you may have lichen sclerosus, your doctor can discuss treatment options with you.

Can I use Dermovate on my private parts?

Yes, Dermovate can be used to treat conditions that affect the vulval skin, including lichen sclerosus and lichen planus, but you should only do so if your doctor has prescribed it for this purpose.

Medical review byDr. Caroline FontanaLast review 27 February 2026
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Dermovate Overview

Type of medicine Topical steroid
Used for Eczema and psoriasis
Active ingredient Clobetasol proprionate
Works by Blocking chemicals that cause inflammation
Effective within 4 weeks
Available as Ointment, cream
Available dosages 0.05% clobetasone proprionate
Usage instructions Apply a thin layer to affected areas once or twice daily
Packaging A cardboard carton containing a plastic tube
Manufacturer Glaxo Wellcome
Generic available No

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

How does it work?

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Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
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Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
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Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

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Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!