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EMLA Cream

Premature Ejaculation|Active ingredient(s): Lidocaine & prilocaine|Manufacturer: Aspen Pharma

A smiling couple on the bed

Last up to 10 minutes longer with EMLA numbing cream

  • Clinically proven to help men last longer in bed
  • Reduces sensitivity without numbing sensation completely
  • Fast-acting local anaesthetic—works in as little as 15 minutes
  • Easy-to-apply topical cream
  • 5% cream containing lidocaine and prilocaine

How to use

A fingertip with a small amount of cream on it

Apply the cream

Apply a pea-sized amount of cream to the head of the penis 15-30 minutes before sex.

A hand touching the minute hand of a clock on a blank background

Let it absorb

Leave EMLA cream on for 15-30 minutes so it can get to work. It should make the penis less sensitive, but won’t numb it completely.

Hands being washed with soap in a sink

Wash thoroughly before sex

Wash it off completely with soap and water before sex.

What others say about EMLA Cream

Trustpilot review
2 reviews with score 4

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Price is all-inclusive.
Consultation is included.
Prescription is included.

Free shipping.
UK: Free next-day delivery.
Discreet packaging.

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Certified online pharmacy.

EMLA Cream

What is EMLA cream?

EMLA (Eutectic Mixture of Local Anaesthetics) is an anaesthetic cream containing lidocaine and prilocaine that numbs the skin. It is used for a number of reasons, but is prescribed off-label to treat premature ejaculation. When applied to the penis before sex, it numbs the skin so that you can last longer during sex.

What is EMLA cream used for?

EMLA cream is used to numb the skin to reduce pain or sensitivity for several medical reasons. Common uses include:

  • Before injections or minor procedures.
  • To reduce irritation from skin procedures such as tattooing.
  • To help delay ejaculation.

At 121doc, we prescribe EMLA cream off-label for the treatment of premature ejaculation.

How does EMLA cream work for premature ejaculation?

EMLA cream works by blocking pain signals where it is applied. This numbs the skin, helping you last longer in bed.

Here’s a step-by-step guide on how it works:

  1. EMLA cream is absorbed: The active ingredients, lidocaine and prilocaine, are absorbed into the skin within 15-30 minutes.
  2. It numbs the skin: This partially blocks the nerve endings, which numbs the area and reduces signals sent to the brain.
  3. Sensitivity is reduced: The penis becomes less sensitive, helping you last longer during sex without removing sensation entirely.

How effective is EMLA cream for premature ejaculation?

EMLA cream 5% is clinically proven to prolong ejaculation for up to 10 minutes.

In a study of 40 men with premature ejaculation, applying EMLA cream 30 minutes before sex increased the time taken to ejaculate by an average of 8 minutes and 42 seconds, with some participants even lasting 10 minutes or longer. This is generally how well EMLA works, but some patients may respond to treatment better or worse.

How do I apply EMLA cream?

Follow these instructions when applying EMLA cream:

  1. Squeeze a pea-sized amount of cream onto your fingertip
  2. Apply the cream to the affected area 15-30 minutes before sex
  3. Wash your hands with soap and water once the cream has been applied
  4. Wash the cream off your penis before having sex

Please note: If any amount of cream gets in your eyes, wash them thoroughly with saline solution.

How long does EMLA cream take to work?

EMLA numbing cream works best when applied 15-30 minutes before sexual activity. This gives the ingredients enough time to take effect, but not too long for it to numb the penis too much and cause problems getting an erection.

Individual responses to treatment may differ. Work with your doctor to find what works best for you.

How long does EMLA cream last?

The numbing effects of EMLA cream can last for up to 1-2 hours after you remove it, but this largely depends on how long you leave it on for. For best results, leave it on for 15-30 minutes and have sex soon after it has been washed off.

One study showed that EMLA cream applied too early (more than 30 minutes before sex) caused some patients to have difficulty maintaining an erection, so make sure you time your application well.

Who can use EMLA cream?

Only men aged 18 or over with premature ejaculation can be prescribed EMLA cream from 121doc.

Do not use it if you are allergic to any ingredient found in this medicine. Additionally, check with your doctor first if you have:

  • a rare inherited illness known as ‘glucose-6-phosphate dehydrogenase deficiency’
  • a problem with blood pigment called ‘methaemoglobinaemia’
  • an itchy skin condition called ‘atopic dermatitis’

What are the side effects of EMLA cream?

EMLA cream side effects include:

  • skin reactions
  • a tingling sensation
  • skin irritation

Not everyone will experience side effects, and some mild skin reactions are just a sign the cream is working. Check with your doctor if you are worried about your reaction to treatment.

For a full list of side effects, consult the patient information leaflet.

Can I use condoms after applying EMLA cream?

Avoid using latex condoms with EMLA as oil-based creams can weaken the plastic and make them more likely to break. This can increase the risk of unintended pregnancy. Instead of latex, try polyurethane condoms, which are more durable and less likely to break during sex.

Can I use EMLA with other premature ejaculation treatments?

Yes, you can generally use other treatments like Priligy (Dapoxetine) alongside EMLA, but you should check with your doctor first. Some healthcare providers may recommend both treatments together if they are ineffective alone, but this is subject to prescription.

Is EMLA the same as lidocaine?

No, EMLA is not the same as lidocaine, although it does contain lidocaine as well as prilocaine as one of its active ingredients. Lidocaine and prilocaine are local anaesthetics that numb the skin, causing men to last longer in bed when applied to the penis.

Can I get EMLA cream over the counter?

No, you cannot get EMLA cream without a prescription from a licensed healthcare provider. Safety is our number one priority at 121doc, and our doctors will only prescribe treatment if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects
Medical review byDr. Caroline FontanaLast review 03 December 2025
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

EMLA Cream Overview

Type of medicine Local anaesthetic cream
Used for Premature ejaculation
Active ingredient Lidocaine/Prilocaine
Works by Temporarily numbing the penis by blocking nerve signals, helping you to last longer during sex
Effective within 15-30 minutes after application
Available as Topical cream
Available dosage(s) 2.5% lidocaine/2.5% prilocaine
Usage instructions Apply to the head of the penis 15-30 minutes before sex. Wash it off with soap and water before you begin
Packaging 5 g tube of cream
Manufacturer AstraZeneca
Generic available? No
Storage Store below 30°C in the original packaging

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

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Every order includes:

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All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

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All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

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As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

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If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

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Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

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With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

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