EMLA Cream
Premature Ejaculation|Active ingredient(s): Lidocaine & prilocaine|Manufacturer: Aspen Pharma
What others say about EMLA Cream
It is packaged well and I hope it's long term benefits are good.
Everything is fine, quick service.
Excellent, punctual service, as always. I'll be back in the near future with a new order.
The service from 121doc is really fast reliable and very friendly customer chat team. Have no cons. All pros 5star service from order to delivery
Very efficient and professional service. Helpful and proactive. Happy to recommend.
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Price is all-inclusive.
Consultation is included.
Prescription is included.
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UK: Free next-day delivery.
Discreet packaging.
Licensed doctors.
Registered pharmacies.
Certified online pharmacy.
EMLA Cream
What is EMLA cream?
EMLA (Eutectic Mixture of Local Anaesthetics) is an anaesthetic cream containing lidocaine and prilocaine that numbs the skin. It is used for a number of reasons, but is prescribed off-label to treat premature ejaculation. When applied to the penis before sex, it numbs the skin so that you can last longer during sex.
What is EMLA cream used for?
EMLA cream is used to numb the skin to reduce pain or sensitivity for several medical reasons. Common uses include:
- Before injections or minor procedures.
- To reduce irritation from skin procedures such as tattooing.
- To help delay ejaculation.
At 121doc, we prescribe EMLA cream off-label for the treatment of premature ejaculation.
How does EMLA cream work for premature ejaculation?
EMLA cream works by blocking pain signals where it is applied. This numbs the skin, helping you last longer in bed.
Here’s a step-by-step guide on how it works:
- EMLA cream is absorbed: The active ingredients, lidocaine and prilocaine, are absorbed into the skin within 15-30 minutes.
- It numbs the skin: This partially blocks the nerve endings, which numbs the area and reduces signals sent to the brain.
- Sensitivity is reduced: The penis becomes less sensitive, helping you last longer during sex without removing sensation entirely.
How effective is EMLA cream for premature ejaculation?
EMLA cream 5% is clinically proven to prolong ejaculation for up to 10 minutes.
In a study of 40 men with premature ejaculation, applying EMLA cream 30 minutes before sex increased the time taken to ejaculate by an average of 8 minutes and 42 seconds, with some participants even lasting 10 minutes or longer. This is generally how well EMLA works, but some patients may respond to treatment better or worse.
How do I apply EMLA cream?
Follow these instructions when applying EMLA cream:
- Squeeze a pea-sized amount of cream onto your fingertip
- Apply the cream to the affected area 15-30 minutes before sex
- Wash your hands with soap and water once the cream has been applied
- Wash the cream off your penis before having sex
Please note: If any amount of cream gets in your eyes, wash them thoroughly with saline solution.
How long does EMLA cream take to work?
EMLA numbing cream works best when applied 15-30 minutes before sexual activity. This gives the ingredients enough time to take effect, but not too long for it to numb the penis too much and cause problems getting an erection.
Individual responses to treatment may differ. Work with your doctor to find what works best for you.
How long does EMLA cream last?
The numbing effects of EMLA cream can last for up to 1-2 hours after you remove it, but this largely depends on how long you leave it on for. For best results, leave it on for 15-30 minutes and have sex soon after it has been washed off.
One study showed that EMLA cream applied too early (more than 30 minutes before sex) caused some patients to have difficulty maintaining an erection, so make sure you time your application well.
Who can use EMLA cream?
Only men aged 18 or over with premature ejaculation can be prescribed EMLA cream from 121doc.
Do not use it if you are allergic to any ingredient found in this medicine. Additionally, check with your doctor first if you have:
- a rare inherited illness known as ‘glucose-6-phosphate dehydrogenase deficiency’
- a problem with blood pigment called ‘methaemoglobinaemia’
- an itchy skin condition called ‘atopic dermatitis’
What are the side effects of EMLA cream?
EMLA cream side effects include:
- skin reactions
- a tingling sensation
- skin irritation
Not everyone will experience side effects, and some mild skin reactions are just a sign the cream is working. Check with your doctor if you are worried about your reaction to treatment.
For a full list of side effects, consult the patient information leaflet.
Can I use condoms after applying EMLA cream?
Avoid using latex condoms with EMLA as oil-based creams can weaken the plastic and make them more likely to break. This can increase the risk of unintended pregnancy. Instead of latex, try polyurethane condoms, which are more durable and less likely to break during sex.
Can I use EMLA with other premature ejaculation treatments?
Yes, you can generally use other treatments like Priligy (Dapoxetine) alongside EMLA, but you should check with your doctor first. Some healthcare providers may recommend both treatments together if they are ineffective alone, but this is subject to prescription.
Is EMLA the same as lidocaine?
No, EMLA is not the same as lidocaine, although it does contain lidocaine as well as prilocaine as one of its active ingredients. Lidocaine and prilocaine are local anaesthetics that numb the skin, causing men to last longer in bed when applied to the penis.
Can I get EMLA cream over the counter?
No, you cannot get EMLA cream without a prescription from a licensed healthcare provider. Safety is our number one priority at 121doc, and our doctors will only prescribe treatment if you meet the criteria in your online consultation.
A prescription from a trusted healthcare provider like 121doc ensures:
- safety during treatment
- effective results
- monitoring of side effects

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.
EMLA Cream Overview
| Type of medicine | Local anaesthetic cream |
| Used for | Premature ejaculation |
| Active ingredient | Lidocaine/Prilocaine |
| Works by | Temporarily numbing the penis by blocking nerve signals, helping you to last longer during sex |
| Effective within | 15-30 minutes after application |
| Available as | Topical cream |
| Available dosage(s) | 2.5% lidocaine/2.5% prilocaine |
| Usage instructions | Apply to the head of the penis 15-30 minutes before sex. Wash it off with soap and water before you begin |
| Packaging | 5 g tube of cream |
| Manufacturer | AstraZeneca |
| Generic available? | No |
| Storage | Store below 30°C in the original packaging |
FAQs
What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.
Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.
How does it work?
What you need treatment for:
On each page, we provide information as well as treatment options we currently offer. To begin your consultation, select what you need treatment for from the top menu and simply choose "Start consultation" on the selected page.
Treatments:
You can read more about our treatment options on our treatment information pages. To search for a specific medication, simply use the search function.
You will be presented with your recommended treatment option(s) after completing your online consultation.
Ordering:
Every order starts with an online consultation. We will ask you medical questions to make sure that only treatments that are safe and effective are prescribed. We take into account your lifestyle, health and any other medications you’re currently using.
The consultation is completely free and takes between 5 and 10 minutes of your time.
All your information is safe with us. We don’t share it with anyone unless you want us to.
Help:
If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.
Review:
As soon as you place your order, one of our doctors will review your consultation.
Questions:
If the doctor has any additional questions, you will receive a phone call or an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can contact you at a more convenient time if necessary.
Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).
Pharmacy:
Once our pharmacy receives your prescription and dispatches your treatment, you will receive a second email with the tracking number.
Always free. Discreet packaging.
Free:
Express delivery is included with all orders. Alternatively, you can select a delivery date that suits you better.
Convenient:
You can check the estimated delivery time using your tracking number. All we need is your signature (or a friend's or family member's).
Discreet:
All parcels are plainly labelled; there is no logo or any indication of their contents.
Repeat:
With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.
The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.
Subscribe:
There are two ways to subscribe. The first is during the order process. The second is via your profile here.
You can cancel or amend your repeat prescriptions at any time.
Save:
There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!