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Dymista Nasal Spray

Hay Fever|Active ingredient(s): Fluticasone propionate & Azelastine|Manufacturer: Novo Nordisk

A woman using a nasal spray.

Non-drowsy antihistamine for fast, effective hay fever relief

  • Hay fever relief within 5 minutes
  • Combines an antihistamine and corticosteroid for dual-action symptom relief
  • Targets sneezing, runny nose, itchy eyes, and nasal congestion
  • Non-drowsy formula suitable for daily use
  • Available as a nasal spray (137 mcg/50 mcg per spray)

How to use

A fine mist being released from the tip of a nasal spray

Prime your spray

Gently shake the bottle for 5 seconds. Then, if using your spray for the first time, press the pump until a fine mist is released into the air.

A woman blowing her nose into a tissue

Clear your nose

Blow your nose gently into a tissue to clear your nose and ensure the medicine is ingested successfully.

A woman holding a nasal spray to her nose

Use your spray

Insert the device into one of your nostrils and push down on the pump while breathing in gently through your nose.

What others say about Dymista Nasal Spray

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11,238 reviews with score 4.5

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Price is all-inclusive.
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Prescription is included.

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UK: Free next-day delivery.
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Dymista Nasal Spray

What is Dymista?

Dymista is an antihistamine nasal spray manufactured by Viatris. Sprayed directly up the nose, it helps relieve nasal congestion and other symptoms of hay fever, such as sneezing, itchy or watery eyes, and a runny nose.

At 121doc, we prescribe Dymista nasal spray in the 137 mcg/50 mcg dose for people aged 18 or older with hay fever.

How does Dymista work?

Dymista works in two ways to relieve allergy symptoms. One ingredient, azelastine, blocks a chemical called histamine, which your body produces to fight things you are allergic to, such as pollen. Medicines that work in this way are called antihistamines. The other ingredient, fluticasone, is a steroid that reduces inflammation and congestion in the nasal passages.

This dual-action formula stops your body from overreacting to allergens while also soothing inflammation for easier breathing.

What is Dymista used for?

Dymista nasal spray is used for moderate-to-severe allergic rhinitis (hay fever). This can be seasonal or all-year-round (perennial), and can be used for as long as symptoms are present, given your doctor says it is okay.

Is Dymista good for sinus infections?

Dymista is not licensed to treat sinus infections and will not be very effective for this purpose. While it can help alleviate some of the symptoms of a sinus infection, such as congestion and a runny nose, due to its anti-inflammatory effect, it will not treat the infection itself.

Usually, sinus infections should clear on their own within 1-2 weeks. Speak with your doctor or pharmacist for advice on treatment if it doesn’t go away during this time.

How do I use Dymista nasal spray?

Follow these instructions on how to use your Dymista nasal spray:

step 1

Prepare your spray

Shake the bottle for 5 seconds, then remove the cap

step 2

Prime the bottle

If using Dymista for the first time or if it hasn’t been used for more than 7 days, press down on the pump until a fine mist is released into the air

step 3

Blow your nose

Gently blow your nose into a tissue

step 4

Insert the nozzle

Close one nostril with your finger and insert the tip of the nozzle into your other one.

step 5

Spray your dose

Press down on the pump while breathing in gently through your nose

step 5

Repeat

Insert the nozzle into your other nostril and spray again, breathing in as you do it

How often should I use Dymista?

Dymista nose spray is usually prescribed seasonally when pollen counts are high, and is generally safe to take for up to 6 months. If you have perennial hay fever, a chronic condition causing allergy symptoms all year, you may be prescribed Dymista for longer, but this must be done under a doctor’s supervision.

How long does Dymista take to work?

Dymista can work in as little as 5 minutes to relieve hay fever symptoms; however, most people feel significant relief within 15-30 minutes. For peak effects to be felt, it can take a few days of regular use.

How effective is Dymista?

Dymista is clinically proven to significantly reduce symptoms of hay fever.

In a study of 161 people taking Dymista for hay fever:

  • 89.1% reported well or partially controlled symptoms on day 1
  • Average symptom severity scores fell by roughly 58% after 6 weeks
  • Sleep quality improved significantly

Who can use Dymista?

Dymista is a prescription medication. To be prescribed it, you must be over 18 years old with moderate-to-severe hay fever.

Do not use Dymista nasal spray if you are allergic to azelastine hydrochloride, fluticasone propionate, or any other ingredient found in this medicine. In addition to this, tell your doctor if you have:

  • had a recent operation on your nose
  • an infection in your nose
  • tuberculosis or an untreated infection
  • issues with your vision
  • impaired adrenal function
  • severe liver disease

Can I use Dymista when pregnant or breastfeeding?

Dymista nasal spray can be used when pregnant or breastfeeding, but you need to check with your doctor first. While generally low risk, there is limited information about safety during pregnancy and when breastfeeding.

What are the side effects of Dymista?

Dymista nasal spray can cause some unintended side effects, although not everyone gets them.

The most common Dymista side effects include:

  • nosebleed
  • headache
  • a bitter taste in your mouth
  • an unpleasant smell

For a full list of side effects, consult the patient information leaflet.

Does Dymista help with post-nasal drip?

Yes, Dymista can help with postnasal drip. It does this through its two active ingredients. The antihistamine azelastine reduces allergy-related mucus production, and the corticosteroid fluticasone calms inflammation in the nasal passages. Together, these effects help prevent excess mucus and ease throat irritation, helping with postnasal drip.

How long does Dymista stay in your system?

Dymista stays in your system for up to 48 hours, but the effects typically wear off after about 12 hours. That’s why it’s typically taken twice daily for 24-hour hay fever control. Peak effects are felt after a few days of use, after which symptom control is consistent.

Is Dymista a steroid?

Dymista contains two ingredients, one of which is a corticosteroid (steroid). Fluticasone propionate reduces inflammation in the airways to ease congestion and soothe hay fever symptoms. The other ingredient, azelastine hydrochloride, is an antihistamine that blocks the chemical responsible for allergy symptoms.

Can you buy Dymista over the counter?

No, you cannot get Dymista spray without a prescription from a licensed healthcare provider. Safety is our number one priority at 121doc, and our doctors will only prescribe treatment if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects

To see if you’re eligible for treatment, all you have to do is complete a short online consultation. If approved by our medical team, your treatment will be delivered direct to your door in discreet packaging.

Medical review byDr. Caroline FontanaLast review 06 March 2026
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Dymista Nasal Spray Overview

Type of medicine Antihistamine and corticosteroid
Used for Hay fever
Active ingredient Azelastine hydrochloride & fluticasone propionate
Works by Blocking the effects of histamine and reducing inflammation in the nasal passages
Effective within 15-30 minutes
Available as Nasal spray
Available dosage(s) 137 mcg azelastine hydrochloride/50 mcg fluticasone propionate
Usage instructions Spray once into each nostril twice daily
Packaging 25 ml nasal spray bottle
Manufacturer Viatris
Generic available? No
Storage Store upright in the original packaging. Do not refrigerate or freeze

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

How does it work?

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Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
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Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

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Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!