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Rabeprazole

Acid reflux and heartburn|Active ingredient(s): Rabeprazole|Manufacturer: Accord

A man taking a tablet for acid reflux symptoms

Fast-acting heartburn relief with a daily tablet

  • Eases symptoms like heartburn and indigestion
  • Faster onset-of-action than other acid reflux treatments
  • Short-term or long-term treatment for acid reflux symptoms
  • Well-tolerated by most people, with lower potential for drug interactions
  • Available in 10 mg or 20 mg gastro-resistant tablets

How to use

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Take your tablet(s)

Take 1 tablet either once or twice daily. Your doctor will tell you your dosage. Take your tablets whole before you eat and with a glass of water.

Close up of a female hand pushing away a plate of unhealthy foods

Avoid triggers

Rabeprazole reduces stomach acid by itself, but you can make treatment even more effective by staying healthy and avoiding acid reflux triggers.

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Continue treatment

Follow your prescription for as long as your doctor has prescribed it for. For acid reflux, treatment is usually 4-8 weeks.

What others say about Rabeprazole

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Rabeprazole

What is Rabeprazole?

Rabeprazole, sometimes sold under the brand name Pariet, is a prescription medication used to treat acid reflux and heartburn. When taken daily, it reduces stomach acid to prevent it from travelling up the oesophagus, treating symptoms like heartburn and indigestion.

Rabeprazole gastro-resistant (delayed-release) tablets are available in 10 mg or 20 mg doses, which you can order from 121doc after a short online consultation.

Is Rabeprazole the same as Pariet?

Yes, Rabeprazole and Pariet are the same medicine. They contain the same active ingredient (rabeprazole sodium), and work in the same way to ease acid reflux symptoms. They do differ, however, in price, packaging, and manufacturer, with generic Rabeprazole generally being the more affordable option while being just as effective.

How does Rabeprazole work?

Rabeprazole works by reducing the amount of acid produced in the stomach, making it less likely to travel up the oesophagus (food pipe) and cause painful symptoms like heartburn. It does this through its active ingredient, rabeprazole sodium.

When ingested, rabeprazole sodium targets cells in the stomach known as proton pumps, which are responsible for producing stomach acid. Medicines that work in this way are known as proton pump inhibitors (PPIs), and are the most commonly-prescribed treatment for moderate-to-severe cases of acid reflux or GORD (gastro-oesophageal reflux disease).

How effective is Rabeprazole?

Rabeprazole is proven effective in clinical trials, offering consistent relief from symptoms of acid reflux. In one study of patients with GORD treated with Rabeprazole 20 mg:

  • 83% of days were free from heartburn
  • 84% of daytime hours were heartburn-free
  • 95% of nighttime hours were heartburn-free

These results show Rabeprazole offers reliable acid reflux control, day and night.

Who can use Rabeprazole?

To be prescribed Rabeprazole from 121doc, you must be over 18 years old and you must suffer from symptoms of acid reflux.

Do not take Rabeprazole if you are:

  • allergic to rabeprazole sodium or any other ingredient found in this medicine
  • pregnant or breastfeeding

In addition to this, there are some circumstances where a doctor will prescribe Rabeprazole on a case-by-case basis. Consult your doctor before taking Rabeprazole if you:

  • are allergic to another proton pump inhibitor
  • have a stomach tumour
  • have ever had liver disease
  • take Atazanavir (a HIV medication)
  • have a specific blood test coming up (Chromagranin A)

What are the side effects of Rabeprazole?

Taking Rabeprazole for acid reflux can cause some side effects, although not everyone will get them. For most, side effects will be mild and temporary. For others, they may be more severe.

The most common side effects of Rabeprazole include:

  • increased risk of infection
  • insomnia
  • headaches
  • dizziness
  • a cough or sore throat
  • diarrhoea or vomiting
  • back pain
  • pain with an unknown cause
  • feeling weak

This is not an exhaustive list. For a full list of Rabeprazole side effects, consult the patient information leaflet.

How long can I take Rabeprazole for?

Rabeprazole can be taken long-term if necessary, but most prescriptions for acid reflux will last for 4-8 weeks. This is usually enough time to reduce excess stomach acid to a healthy level, bring symptoms under control, and allow the oesophagus to heal. Taking this treatment long-term risks vitamin B12 deficiency and low magnesium.

Your doctor will determine a safe length of treatment with Rabeprazole and prescribe based on your condition and medical history.

What’s the best time of day to take Rabeprazole?

The best time of day to take Rabeprazole depends on how often you take it, and on your doctor’s advice. In general, for those taking it once per day, it’s best to take Rabeprazole in the morning 30-60 minutes before you eat. For twice-daily dosing, take one tablet in the morning and one in the evening, before breakfast and dinner, respectively.

You can also take your tablets after meals, but it works best when taken just before eating. This ensures the medicine has a chance to work before the food you eat triggers an increase in stomach acid.

Are Rabeprazole and Pantoprazole the same?

Rabeprazole and Pantoprazole are both proton pump inhibitors that work in the same way to reduce stomach acid, but they are distinct medicines. They differ in their chemical structure, dosage options, manufacturers, and how quickly they take effect, meaning one may be more suitable for you than the other.

Can I take antacids with Rabeprazole?

Yes, you can take antacids alongside Rabeprazole provided your doctor has told you it is safe. This can be particularly helpful when you first begin treatment, before the effects of Rabeprazole can be felt fully. Never take more than the maximum dose of either medicine and always tell your doctor if you plan to take medicines together.

Omeprazole vs Rabeprazole: Which is better?

Both acid reflux treatments work well to protect you from heartburn, but neither is regarded as “better” than the other. Omeprazole is more commonly prescribed and well-studied, whereas Rabeprazole is better tolerated by some with fewer drug interactions. Whichever one you choose, you can usually switch treatments under your doctor’s supervision if you feel the other might suit you better.

Can I buy Rabeprazole over the counter?

No, you cannot get Rabeprazole without a prescription from a licensed healthcare provider. Safety is our number one priority at 121doc, and our doctors will only prescribe treatment if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects

To see if you’re eligible for treatment, all you have to do is complete a short online consultation. If approved by our medical team, you can then buy the acid reflux medication Rabeprazole and it will be delivered direct to your door in discreet packaging.

Medical review byDr. Caroline FontanaLast review 13 February 2026
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Rabeprazole Overview

Type of medicine Proton pump inhibitor
Used for Acid reflux
Active ingredient Rabeprazole sodium
Works by Reducing the amount of acid produced in the stomach
Effective within 2-3 days, with full effects felt within 4 weeks
Available as Gastro-resistant tablets
Available dosage(s) 10 mg, 20 mg
Usage instructions Take 1 tablet once or twice per day (depending on your doctor’s instructions) for the length of time prescribed by your doctor.
Packaging Blister packs containing 28 tablets
Manufacturer Various
Branded available? No
Storage Store below 30°C in the original packaging

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

How does it work?

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Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.

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If you know what you want, the quickest way to find a specific medication is to use the search bar here.

Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
Prescribe Our doctors review your order.
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Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat
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10 to 15% off

Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!