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Omeprazole

Acid reflux and heartburn|Active ingredient(s): Omeprazole|Manufacturer: Various

A man taking a pill for heartburn symptoms

Treats acid reflux at the source to ease heartburn and indigestion

  • Fast relief from acid reflux symptoms
  • Directly reduces stomach acid
  • Once-daily dosing for consistent reflux treatment
  • Flexible dosage options for a range of symptoms
  • Available as 10 mg and 20 mg Omeprazole capsules

How to use

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Take your capsule(s)

Take one or two capsules once daily, depending on your doctor’s advice. Take your capsules whole an hour before you eat with a glass of water.

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Avoid triggers

Omeprazole reduces stomach acid by itself, but you can make treatment even more effective by staying healthy and avoiding acid reflux triggers.

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Continue treatment

Follow your prescription for as long as your doctor has prescribed it for. For acid reflux, treatment is usually 4-8 weeks.

What others say about Omeprazole

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Omeprazole

What is Omeprazole?

Omeprazole is an acid reflux treatment that eases symptoms like heartburn and indigestion. Taken daily, it prevents stomach acid from traveling up the oesophagus, even after eating. It belongs to a group of medicines known as proton pump inhibitors (PPIs).

You can order 10 mg and 20 mg mg Omeprazole gastro-resistant (delayed-release) capsules from 121doc to treat symptoms of acid reflux or GORD (gastro-oesophageal reflux disease).

Is Lansoprazole the same as Omeprazole?

Lansoprazole and Omeprazole are both proton pump inhibitors used to treat acid reflux, but they differ in some key ways. Most notably, they contain different active ingredients. This means if one doesn’t work well for your symptoms the other one might, and being allergic to one doesn’t mean you’re allergic to the other. For these reasons, one treatment may be more suitable for you.

Other ways they differ include manufacturer, packaging, and cost. Take all of these differences into account when deciding which acid reflux treatment is right for you.

What is Omeprazole used for?

Omeprazole is most commonly prescribed as a treatment for acid reflux and heartburn, but its uses don’t end there. Omeprazole is also used for:

  • gastro-oesophageal reflux disease (GORD)
  • ulcers in the upper stomach (gastric ulcer) or intestine (duodenal ulcer)
  • ulcers infected with bacteria called ‘Helicobacter pylori
  • ulcers caused by medicines called NSAIDs (e.g. Ibuprofen)
  • too much stomach acid caused by a growth in the pancreas (Zollinger-Ellison syndrome)

At 121doc, we prescribe Omeprazole specifically for acid reflux.

How does Omeprazole work?

Omeprazole works by blocking the pumps in the stomach (proton pumps) from producing acid. With less stomach acid, less can travel up the food pipe, causing a reduction of symptoms of acid reflux like heartburn and indigestion.

Proton pump inhibitors like Omeprazole are the most commonly prescribed treatment for acid reflux that cannot be treated with antacids alone.

How effective is Omeprazole?

Omeprazole is highly effective in treating symptoms of acid reflux. In one study, 96.4% of patients treated with Omeprazole remained symptom free after 42 weeks of maintenance therapy, showing its usefulness in long-term acid reflux treatment.

How long does Omeprazole take to work?

Omeprazole starts reducing stomach acid quickly, but it typically takes 2-3 days before you begin to notice some relief in symptoms. Full symptom relief should be felt after 4 weeks or so of consistent treatment with Omeprazole. Only take Omeprazole for as long as your doctor has prescribed it for.

Who can use Omeprazole?

To be prescribed Omeprazole from 121doc, you must be over 18 years old and have been diagnosed with acid reflux.

Do not take Omeprazole if you are:

  • allergic to omeprazole or any other ingredient in this medicine
  • allergic to medicines containing other proton pump inhibitors
  • taking a medicine containing nelfinavir (used for HIV)

Tell your doctor about any health condition you have to ensure safe prescribing, even those not mentioned here.

When should I take Omeprazole?

It’s best to take Omeprazole capsules 1 hour before eating, as this ensures the medicine has a chance to work before the food you eat triggers an increase in stomach acid. It is recommended you take it in the morning before breakfast, giving you symptom control throughout the day, although you can take it at any time. Just make sure you take it at the same time every day.

What if I miss a dose of Omeprazole?

If you forget to take a dose on Omeprazole, what you do next depends on how long it has been.

  • If there is over 12 hours until your next scheduled dose: take the missed one straight away, and your next one at the usual time.
  • If it is within 12 hours of your next dose: skip the missed dose and take your next one at the usual time.

Do not take a double dose to make up for a missed one.

What are the side effects of Omeprazole?

Taking Omeprazole for acid reflux can cause side effects, although most are mild and not everyone will experience them.

The most common Omeprazole side effects include:

  • headache
  • diarrhoea
  • stomach pain
  • constipation
  • nausea or vomiting
  • benign polyps (growths) in the stomach

This is not an exhaustive list. For a full list of Omeprazole’s side effects, consult the patient information leaflet.

Does Omeprazole cause constipation?

Yes, Omeprazole can cause constipation in some people. It is listed as a common side effect, affecting up to 1 in 10 people who take the acid reflux medication. It does this because it can slow down digestion and affect gut bacteria.

You can manage constipation as a result of Omeprazole use by drinking plenty of water, eating a high-fibre diet, and getting regular exercise.

Does Omeprazole cause weight gain?

Omeprazole can cause weight gain, but this is exceedingly rare, especially with short-term use. One study has found a link between Omeprazole use and weight gain, but further research is needed before definitive claims can be made. As it stands, weight gain is not listed as a side effect, and any changes in weight are likely a result of changes in diet once symptoms are resolved.

Is Omeprazole safe to take long-term?

It’s typically safe to take Omeprazole for up to a year without any problems. If you need to take it for longer than this, it’s usually fine to do so, but will need to be done under a doctor’s supervision.

Taking a proton pump inhibitor like Omeprazole long-term (over a year) can slightly increase your risk of fracture in the wrist, hip or spine. It can also affect the way your body absorbs vitamin B12, meaning you may need to take some alongside treatment. Tell your doctor if you notice tiredness, pins and needles, a sore or red tongue, muscle weakness, or disturbed vision.

Is 40 mg of Omeprazole a high dose?

Yes, 40 mg Omeprazole is a relatively high dose, and is usually prescribed for stubborn cases of acid reflux where 10 mg or 20 mg is not enough. For most people, the recommended dose is 10 mg or 20 mg once per day.

Can I take Omeprazole while pregnant or breastfeeding?

It is typically safe to take Omeprazole while pregnant or breastfeeding, but you’ll need to confirm this with your doctor before starting treatment. Evidence from limited research seems to suggest Omeprazole is unlikely to cause pregnancy-related problems, but your doctor will need to balance benefits and risks before prescribing treatment.

Can I take Omeprazole and Gaviscon together?

It is typically safe to take Gaviscon with Omeprazole, and many do to maximise the effectiveness of treatment and further ease acid reflux symptoms. However, you should only do so if your doctor has told you it is safe, and you must wait at least two hours between doses.

Can you drink alcohol with Omeprazole?

Generally, yes, you can drink alcohol with Omeprazole, but it is not advised. While alcohol shouldn’t cause serious adverse effects with Omeprazole, it can increase the risk and severity of side effects. If you decide to drink alcohol during treatment, do so in moderation.

Can I buy Omeprazole over the counter?

Yes, you can buy some strengths of Omeprazole from a pharmacist without a doctor’s prescription, but taking it under a doctor’s guidance is still recommended, and higher doses still require a prescription. Safety is our number one priority at 121doc, and our doctors will only approve treatment if you meet the criteria in your online consultation.

A prescription from a trusted healthcare provider like 121doc ensures:

  • safety during treatment
  • effective results
  • monitoring of side effects

To see if you’re eligible for treatment, all you have to do is complete a short online consultation. If approved by our medical team, your treatment will be delivered direct to your door in discreet packaging.

Medical review byDr. Caroline FontanaLast review 17 February 2026
Dr. Caroline Fontana

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Omeprazole Overview

Type of medicine Proton pump inhibitor
Used for Acid reflux
Active ingredient Omeprazole
Works by Reducing the amount of acid produced in the stomach
Effective within 2-3 days, with full effects felt within 4 weeks
Available as Gastro-resistant capsules
Available dosage(s) 10 mg, 20 mg
Usage instructions Take one or two capsules once per day (depending on your doctor’s instructions) for the length of time prescribed by your doctor
Packaging Blister packs containing 28 capsules
Manufacturer Various
Branded available? No
Storage Store below 25°C in the original packaging

FAQs

What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
What services are included with my order?
Is the price all-inclusive?
What are my delivery options?
Is it safe to buy prescription medication online?
Is this service discreet?
What is included in the online consultation?

Our online consultations are in the format of short medical questionnaires. You will be asked general questions about your health and medical history, as well as specific medical questions relevant to the treatment you have chosen. We will also ask you for your payment and delivery details to complete the order.

Online consultations take no longer than 5 minutes to complete. All questions are necessary when issuing prescription medicines. It means that our doctors can make sure the treatment is safe and right for you.

Will a doctor review my consultation?

Yes, it is a legal requirement that all online consultations are reviewed by a registered doctor. This is to make sure the chosen treatment is safe and right for you to take. All personal information is stored securely and confidentially.

Please note, all orders are subject to doctor approval, and we cannot guarantee that your order will be approved.

What happens after I submit my order?

Your online consultation will be sent directly to our medical team, where it will be reviewed by on of our in-house doctors.

If a doctor approves you for treatment, they will issue a prescription. Your prescription will then be forwarded to our pharmacist, where you medication will be dispensed and dispatched for delivery.

What services are included with my order?

Every order includes:

  • Free consultation - your consultation will be personally reviewed by one of our registered doctors.
  • Free prescription - a doctor will issue you a prescription if approved for treatment.
  • Free delivery - we provide free express delivery across Europe, you should receive your order in 1-2 working days.
Is the price all-inclusive?

Yes, our service is all-inclusive and there are no hidden fees. All 121doc orders include a free online consultation, a free prescription and free express delivery.

What are my delivery options?

We offer several delivery options at no extra charge:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not in, a friend or relative can sign in your place.

Is it safe to buy prescription medication online?

It is safe to buy prescription medications online from genuine and reputable healthcare providers, like 121doc.

Our medical staff and facilities are registered with the relevant medical governing bodies. We also ensure your data is protected by adhering to European data privacy laws.

You can learn more about our certifications here.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also closely adhere to data privacy laws.

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

How does it work?

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Conditions:

Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.

Treatments:

If you know what you want, the quickest way to find a specific medication is to use the search bar here.

Ordering:

Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.

Help:

If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe
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Review:

As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.

Questions:

If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).

Pharmacy:

Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver
Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery

Free:

All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.

Location:

We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).

Discreet:

All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat
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10 to 15% off

Repeat:

With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.

Subscribe:

There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.

Save:

There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!