Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How Elleste Solo MX patches Work

The patches provide a natural oestrogen, known as estradiol, via the skin and aim to replace natural hormone that is lost during menopause. The loss of oestrogen is the main reason that women experience symptoms and this treatment aims to correct this imbalance.

Elleste Solo MX just contains natural oestrogen, meaning that women who haven't had a hysterectomy should use an alternative treatment such as Elleste Duet or be prescribed clinical oestrogen additionally.

Who it's for

Elleste Solo MX is usually recommended to women who require relief from night sweats, vaginal itching, vaginal dryness and hot flushes. It can also be used in preventing osteoporosis. It may not be recommended as an HRT treatment for you if you have a history of oestrogen-dependent cancer, circulatory problems, liver disease or you have or have had breast cancer. To find out more about the symptoms of menopause and how you can relieve these, visit our menopause information page.

How to use the patches

Elleste Solo MX packs contain just one type of patch that is either available in a 40mcg or 80mcg dose. This means that the treatment releases 40mcg or 80mcg via the skin into the body every 24 hours. The patch should be applied to an area of skin that is clean and dry and located below the waist. The patch should be changed twice a week and is worn in 28 day cycles, without any breaks between patches.

The side effects

HRT treatments, just like any prescription treatment, have a risk of side effects, however when you have been prescribed the right treatment by your doctor and you are going for regular check-ups these shouldn't be anything to worry about. The common side effects such as nausea, indigestion, headaches, acne, fluid retention, leg cramps and irritation in the area where the patch is applied, are mostly a sign that the body is adjusting to the treatment, but you should tell your doctor if any of the side effects that you are experiencing are causing you significant discomfort.

Ordering online

These patches are available to order from 121doc. We, however, only provide repeat prescriptions for these types of treatments, which is why you should order a medication that you have already been prescribed by your doctor. The ordering process includes a consultation process and any information you provide on this consultation form will be checked by our doctor to make sure that you can use this medication safely. If your consultation is approved your order will be shipped directly to you from our pharmacy for next day delivery.


Overview Oestrogen-only HRT patchesOestrogen-only HRT tablets
Progestogen --
Oestrogen 25 mcg, 50 mcg, 75 mcg, 100 mcg Estradiol every 24h0.3mg, 0.625mg, 1.25mg Conjugated oestrogens
  Active ingredient(s)
Active ingredient(s) EstradiolConjugated oestrogens
  Who can take it
Who can take it If you have had a hysterectomyIf you have had a hysterectomy
Features Alternative to tablets-
  Side effects
Side effects --
  How to take
How to take 1 patch twice weeklyDaily tablet
  Price 3 month course
Price 3 month course £34.99£26.99
View treatmentView treatment

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How does it work?

Select Select your treatment and complete our online consultation.
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Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!