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Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How it works

Anugesic HC helps treat and relieve the symptoms of haemorrhoids in a number of different ways. It starts to work immediately after application by numbing the area with the help of its active ingredient, pramocaine hydrochloride. Pramocaine is a local anaesthetic that stops pain impulses from being transported to the brain.

While proamocaine takes care of any immediate itching and pain, hydrocortisone works to prevent the release of chemicals by the immune system that causes swelling. It may take a few days for swelling to go down, but once it's under control, it's easier for the body to recover naturally, especially if you are taking steps to deal with the initial cause of the piles in the first place.

Who can use it?

Anugesic HC is very safe to use in general, but there are a few instances where it is not advisable to use this treatment. You should not use this if you are allergic to the active ingredient or you have a viral, fungal or bacterial infection that your doctor is not aware of. You should be particularly wary of using this medication if you are experiencing an outbreak of genital warts.

We ask all our patients to complete a confidential consultation if they would like to order this online with us. Make sure that you complete all the questions as thoroughly as possible as our doctor will require this information to make the safest recommendation for you.

Using Anugesic HC

This cream can be applied internally as well as externally with the help of a specially designed rectal nozzle. You should apply this treatment twice a day after every bowel movement.

You should not continue with this treatment for longer than seven days without speaking to a doctor.

The side effects

Side effects are very rare, because it's only applied in the area where it's required and used only for short periods of time. Some of the most common side effects include mild itching or irritation in the area where it has been applied. This should go away within a few days, but if your symptoms persist, they start worrying you or you start to develop something more serious, you should speak to your doctor.

Buying Anugesic HC online

You can order this cream online at 121doc. All you need to do is complete a confidential online consultation form as part of your order. This will be evaluated by our doctor, who will then provide a prescription for our pharmacist. Once your order is dispensed it will be shipped via secure overnight delivery, at no additional charge to you. We offer a number of treatments online at 121doc. Visit our haemorrhoids treatment page for information on the available prescription medications we offer.


Anusol HCBetnovateXyloproctProctofoam HC
Overview Haemorrhoid treatmentHaemorrhoid treatmentHaemorrhoid treatmentHaemorrhoid treatment
  Type of treatment
Type of treatment Topical treatmentTopical treatmentTopical treatmentTopical treatment
  Active ingredient(s)
Active ingredient(s) Hydrocortisone AcetateBetamethasone valerate Lidocaine & Hydrocortisone acetateHydrocortisone acetate & Pramoxine hydrochloride
Features Five active ingredients that relieve discomfort externally & internallySoothes external itch & irritationUsed internally & externally to reduce pain & itchingUsed internally & externally to reduce pain & itching
Breastfeeding UnsuitableCautionCautionCaution
Pregnant UnsuitableCautionCautionCaution
Application OintmentOintment, cream, lotionOintmentFoam
  How to take
How to take Apply directly to the affected area. Apply directly to the affected area. For external use only.Apply directly to the affected area. Apply directly to the affected area.
  Pricing starts at
Pricing starts at £24.99£19.99£29.99£29.95
View treatmentView treatmentView treatmentView treatment

Other treatments that might interest you

Various treatments available

We offer many treatments to manage high blood pressure.

  • Lowers high blood pressure
  • No doctor appointment required
  • Treatment for post-heart attack

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How does it work?

Select Select your treatment


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Redeem your prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!

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