Combined Pill | Active ingredient(s): Ethinylestradiol & Norethisterone acetate | Manufacturer: Galen

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  • Review by a qualified doctor
  • Including prescription
  • Next-day delivery included

How does Loestrin work?

As a combined oral contraceptive, Loestrin contains synthetic forms of both oestrogen and progestogen. This means that it is slightly more effective than some of the progestogen only mini-pills that are available. Combined contraceptive treatments work by manipulating the female menstrual cycle to prevent pregnancy. With almost complete success at doing so, Loestrin is one of the most effective contraceptive methods available.

Loestrin, like other combined contraceptive pills, works to prevent pregnancy in three separate ways. One of the main effects of this treatment is that it tricks the body into believing that an egg has been released. During the female cycle, the levels of naturally occurring hormones change, causing an egg to be released by the ovaries in a process that is known as ovulation. By making the body think ovulation has already occurred, Loestrin prevents this from happening.

Loestrin also works in some other ways to prevent pregnancy. This treatment alters the lining of the womb, which is where potential eggs would develop. This has the effect of making the environment inhospitable for any eggs that may be released. Loestrin also increases the thickness of the naturally occurring vaginal fluids, making it almost impossible for sperm to enter the womb. This three-stage approach makes Loestrin an effective hormonal contraceptive treatment for women.

What are the benefits of Loestrin?

This treatment offers over 99% protection against pregnancy. This means that when you use Loestrin correctly, you will have less than a 1% chance of falling pregnant. This medication also has a lower dosage of hormones than some of its counterparts, which makes it suitable for women who may have experienced side effects from some of the other combined contraceptive pills.

Loestrin can also benefit women who are experiencing heavy or painful bleeds. Most combined contraceptive pills usually cause lighter and more regular menstrual bleeding. Loestrin can also have a positive effect on acne, with women using this medication displaying a reduction in the visible symptoms of this condition.

Who can use Loestrin?

As this treatment contains a lower dosage of hormones, women who may be sensitive to some of the other combined pills can use it. This treatment can used by the majority of healthy women who are over the age of 18 and who would like to use a hormonal contraceptive method.

There are women who may not be suitable for Loestrin. Women who are either pregnant or breast-feeding should not use this treatment. It should also not be used by women over the age of 50. If you have reached 50 and are not yet at menopause, you should consult with your doctor to find the right contraceptive treatment for you.

You may also not be suitable for Loestrin if you have a history of severe diabetes, hypertension, high cholesterol, severe migraines or unexplained vaginal bleeding. You must include any conditions that you are currently suffering from on the online medical form that you will complete as part of the ordering process. Some medications may reduce the effectiveness of this treatment, so include any medications that you are currently taking.

How do you use Loestrin?

Loestrin is a monophasic contraceptive pill, which means that each tablet contains the same dosage of hormones. As with other combined contraceptive pills, you will need to take one tablet a day for a 21 day period, which is then followed by a seven-day break. You may experience a withdrawal bleed during this break but you will still be protected from pregnancy. You should ensure that you take each Loestrin pill at roughly the same time each day.

This treatment is only effective when taken as per the instructions. You should ensure that you do not miss any days and take each pill at the correct time. When you buy Loestrin online at 121doc, you will be provided with the patient leaflet for this medication. You should read this leaflet before beginning the treatment, as it contains detailed instructions on how and when to take this pill. You should refer to this leaflet for instructions on what to do if you miss a pill. You are able to download this patient leaflet from our website at any point.

Are there any side effects?

As this medication contains a lower dosage of hormones, it is generally very well tolerated. As with all prescription medication, there is a risk of side effects in very rare cases. These can include nausea, headaches, breast tenderness, weight fluctuations and irregular bleeding. These side effects are normally temporary and should pass within a few weeks. If you experience anything that causes you significant discomfort when using Loestrin, you should immediately consult with your doctor.

How to buy Loestrin online?

Our core focus is to allow our customers to receive the medication they need as quickly and efficiently as possible. You can buy Loestrin online at 121doc without a face-to-face doctor's appointment or previous prescription. Instead, our doctors have created a quick online medical questionnaire, which they will use to determine whether this is a suitable treatment option for you. Once your order is placed, our doctors will immediately review your details and, if they approve the order, will create a prescription for you. We offer fast and discreet delivery options at no further cost, allowing you to receive your order as quickly as possible.

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.


What is included in the online consultation?
Will a doctor review my consultation?
What happens after I submit my order?
Is the price all-inclusive?
Can I place more than one order at a time?
What are my delivery options?
Is it safe to buy prescription medication online?
How do I know which treatment is best for me?
Is this service discreet?
What is included in the online consultation?

Our consultations include general questions about your health (e.g. blood pressure levels, current and past conditions), as well as specific questions related to your selected treatment. We will also request relevant personal information to complete payment and delivery.

All questions are necessary, and your answers and details will not be shared with any third-parties. Only our doctors have access to your medical information.

Will a doctor review my consultation?

It is a legal and medical requirement that a doctor first reviews all completed consultations. We have a team of in-house doctors and specialists who will ensure your selected treatment is safe for your use. All information is stored securely and confidentially.

Please note, we do not guarantee that our doctors will approve treatment.

What happens after I submit my order?

Your consultation will be sent directly to our medical team, where it will be reviewed by one of our doctors.

If your chosen treatment is deemed suitable for your use, they will issue a prescription. Your prescription is then forwarded to our pharmacy, where your medication will be dispensed and dispatched for courier delivery.

Is the price all-inclusive?

Yes. All 121doc orders include a medical consultation, a prescription and next-day delivery. There are no additional costs. We believe in providing a safe and easy-to-use service.

Can I place more than one order at a time?

Yes. However, certain medications may negatively interact with each other. Our doctors may not approve your order on this basis.

You can place multiple items in one basket, and complete a consultation for all.

If you wish to place a second order for a different medication, you will have to complete a separate consultation.

What are my delivery options?

We offer several delivery options:

  • Next-day delivery
  • UPS Access Point - convenient parcel drop-off and collection near your home or work address
  • Nominated-day delivery - choose the most convenient day for delivery

All these options can be tracked and require a signature on delivery. If you are not available, a friend or relative can sign in your place.

None of these options will incur an additional charge.

Is it safe to buy prescription medication online?

To ensure you are purchasing from a reputable company, you should look to see their country’s regulatory bodies verify them.

In the UK, this is the Care Quality Commission (CQC) and the Medicines and Healthcare products Regulatory Agency (MHRA).Certificates can be viewed here.

How do I know which treatment is best for me?

Some treatments also offer the 'Advise Me' function. You will be asked questions about your lifestyle and needs, plus medical questions. You will then be presented with the advice of our doctors.

Is this service discreet?

Our patients’ privacy is of utmost importance. All your medical information is securely stored and only viewed by our doctors. We do not share your details with third-parties. We are also regularly inspected by various UK regulatory agencies, such as the Information Commissioner's Office (ICO).

All orders will only show on invoices, bank statements, etc. as ‘HHC Ltd’.

What others say about us

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How does it work?

Select Select your treatment and complete our online consultation.
Free consultation


Select a condition here or use the top menu. For every condition, we provide you with information as well as the treatments we currently offer. If you don’t know which is best for you, just click the 'Advise-me' button.


If you know what you want, the quickest way to find a specific medication is to use the search bar here.


Every order starts with an online consultation. We will ask you medical questions to make sure only treatment that is safe and effective is prescribed. We take into account your lifestyle, health and any other medications you’re currently using.

The consultation is completely free, and takes between 5 and 10 minutes of your time.

All your information is safe with us. We don’t share it with anyone unless you want us to.


If you need any guidance, you can call, message or email our customer service team via the ‘How can we help you?' section here.

Prescribe Our doctors review your order.
Free prescription


As soon as you place the order, one of our doctors will review your consultation. On working days, this usually takes around one hour.


If the doctor has any additional questions, you will receive a phone call and an email. We understand you might be at work or busy. Our customer service representatives are always discreet and can call back at a more convenient time if necessary.

Our emails never contain any personal or medical information, only a link to your private account on our website (where you will find your messages).


Once our pharmacy receives your prescription, you will get a second email with your package tracking code.

Deliver Expect your delivery the next working day.
Always free. Discreet packaging.
Free next-day delivery


All orders include next-day delivery. Alternatively, you can select a delivery date that suits you better.


We also provide a free UPS Access Point service. Pick up your package from one of many collection points across the UK.

With your tracking code, you will know the estimated delivery time. All we need is your signature (or a friend‘s or relative’s).


All parcels are plainly labelled; there is no logo or any indication of its contents. Inside, you will find your treatment as well as a patient leaflet in your chosen language.

Repeat Subscribe and save with our repeat service. Never miss a dose again.
10 to 15% off


With 121doc’s Subscribe & Save service, you can automatically receive your treatment every few weeks or months.

The order will be generated by us, using the information you provided (including delivery frequency). You don’t have to do anything. Payment is taken two days before shipping.


There are two ways to subscribe. The first is during the order process. The second is via your profile here.

You can cancel or amend your repeat prescriptions at any time.


There are no sign-up fees with this service. Plus, you get a 10% discount off all future prescriptions, increasing to 15% after six orders!